Division of Gastroenterology and Hepatology, Mayo Clinic, 200 1st St. SW, Rochester, MN, 55902, USA.
Department of Internal Medicine, Beth Israel Lahey Clinic, Burlington, MA, 01803, USA.
Clin J Gastroenterol. 2021 Aug;14(4):1096-1102. doi: 10.1007/s12328-021-01430-6. Epub 2021 May 17.
Angioedema is a self-limited, localized tissue swelling, resulting from fluid extravasation into interstitial spaces. It may occur in isolation or be accompanied by urticaria and/or anaphylaxis. The phenomenon has been linked to multiple medications, including non-steroidal anti-inflammatory drugs (NSAIDs) and angiotensin-converting enzyme inhibitors (ACEIs). NSAID-induced angioedema is observed in < 0.3% of patients taking NSAIDs. While isolated visceral angioedema has been reported from ACEIs, it has not been documented from NSAID use, particularly aspirin usage. Here, we report a case of isolated visceral angioedema attributed to aspirin use.
血管性水肿是一种自限性的局限性组织肿胀，是由于液体渗出到间质空间引起的。它可以单独发生，也可以伴有荨麻疹和/或过敏反应。这种现象与多种药物有关，包括非甾体抗炎药（NSAIDs）和血管紧张素转换酶抑制剂（ACEIs）。在服用 NSAIDs 的患者中，<0.3%观察到 NSAID 引起的血管性水肿。虽然 ACEIs 报道过孤立性内脏血管性水肿，但从 NSAID 使用，特别是阿司匹林使用中尚未记录到。在这里，我们报告了一例归因于阿司匹林使用的孤立性内脏血管性水肿病例。
