Department of Rheumatology, Endocrinology and Nephrology Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Rheumatology Division, Department of Internal Medicine, Padjadjaran University, Bandung, Indonesia.
Int J Rheum Dis. 2021 Jul;24(7):880-895. doi: 10.1111/1756-185X.14125. Epub 2021 May 17.
Systemic lupus erythematosus (SLE) is a more common autoimmune rheumatic disease in the Asia-Pacific region. The prognosis of SLE remains unsatisfactory in some Asian countries because of delayed diagnosis, limited access to medications, increased complications and issues of tolerability and adherence to treatment. The Asia-Pacific League of Associations for Rheumatology SLE special interest group has recently published a set of consensus recommendations on the management of SLE for specialists, family physicians, specialty nurses, and other healthcare professionals in the Asia-Pacific region. This article reports a systematic literature review of the infective complications of SLE in Asia and evidence for prevention of these infections by pre-emptive antimicrobial therapy and vaccination.
系统性红斑狼疮（SLE）是亚太地区较为常见的一种自身免疫性风湿病。由于诊断延误、药物获取受限、并发症增加以及治疗的耐受性和依从性问题，SLE 在一些亚洲国家的预后仍不理想。亚太风湿病学会联盟（APLAR）SLE 特别兴趣小组最近发布了一套针对亚太地区专家、家庭医生、专科护士和其他医疗保健专业人员的 SLE 管理共识建议。本文报告了对亚洲地区 SLE 感染性并发症的系统文献回顾，以及预防性使用抗菌药物治疗和疫苗接种预防这些感染的证据。
