多发性硬化症是否会增加子痫前期的风险？系统评价和荟萃分析。
Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis.
机构信息
Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
Department of Public Health, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.
出版信息
Hypertens Pregnancy. 2021 Aug;40(3):180-185. doi: 10.1080/10641955.2021.1921792. Epub 2021 May 17.
: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE).: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnant women without it using the fixed-effects model. The measured heterogeneity between studies.: Eight eligible studies (9 cohorts) were included. Pregnant women with MS had no excess risk of PE compared with pregnant women without MS (pooled OR = 0.99, 95% CI: 0.89, 1.09; = 0.00%).: MS is not associated with PE.
我们通过系统回顾和荟萃分析研究了多发性硬化症（MS）是否与子痫前期（PE）的风险相关。从合格的研究中，我们使用固定效应模型比较了患有 MS 的孕妇与没有 MS 的孕妇的 PE 比值比（OR）和置信区间（CI）。研究之间存在异质性。八项合格的研究（9 个队列）被纳入。与没有 MS 的孕妇相比，患有 MS 的孕妇没有更高的 PE 风险（汇总 OR=0.99，95%CI：0.89，1.09；P=0.00）。MS 与 PE 无关。
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