Henneman John R, Johnson Julie A, Minihan Mark A
ILAR J. 2022 Jan 7;61(1):32-39. doi: 10.1093/ilar/ilab015.
Waste disposal in Agricultural Animal High Containment Animal Biosafety Level 3Ag and Animal Biosafety Level 4Ag (ABSL-3Ag and ABSL-4Ag) research facilities necessitates significantly more attention to detail in operations than that required in lower-containment-level laboratories. The unique features and requirements of agricultural-related research involve additional equipment and systems to safely transfer decontaminated waste out of the facility. The waste stream coming from ABSL-3Ag and ABSL-4Ag facilities, or high containment agricultural research waste, consists of many forms and differs from most research facility waste in that it is produced from research with livestock or other species loose housed, with the animal room serving as primary containment. This is in contrast to small laboratory animals being housed in primary containment caging. Waste handling equipment in agricultural research facilities may include autoclaves, effluent decontamination systems, incinerators, high-temperature renderers, alkaline tissue digester systems, high-efficiency particulate air filtration of exhaust and supply air, gas decontamination systems, and laundry facilities. This article focuses primarily on the disposal of waste from ABSL-3Ag livestock facilities, including procedures and lessons learned over 10 years of facility operation.
农业动物高防护水平动物生物安全3级和4级（ABSL - 3Ag和ABSL - 4Ag）研究设施中的废物处理，在操作上比低防护水平实验室需要更加注重细节。与农业相关研究的独特特征和要求涉及额外的设备和系统，以安全地将经过去污处理的废物运出设施。来自ABSL - 3Ag和ABSL - 4Ag设施的废物流，即高防护水平农业研究废物，有多种形式，与大多数研究设施的废物不同，它产生于对散养的家畜或其他物种的研究，动物房作为主要防护设施。这与饲养在主要防护笼中的小型实验动物形成对比。农业研究设施中的废物处理设备可能包括高压灭菌器、废水去污系统、焚化炉、高温提炼器、碱性组织消化系统、排气和送风的高效空气微粒过滤、气体去污系统以及洗衣设施。本文主要关注ABSL - 3Ag家畜设施的废物处理，包括设施运行10年来的程序和经验教训。
