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行前房内注射莫西沙星的白内障超声乳化吸除术顺利完成后出现的单侧急性虹膜透照综合征

Unilateral Acute Iris Transillumination Syndrome following Uneventful Phacoemulsification Surgery with Intracameral Moxifloxacin.

作者信息

Gonul Saban, Eker Serhat

机构信息

Department of Ophthalmology, Selcuk University Faculty of Medicine, Konya, Turkey.

出版信息

Ocul Immunol Inflamm. 2022 Oct-Nov;30(7-8):1984-1987. doi: 10.1080/09273948.2021.1916042. Epub 2021 May 18.

Abstract

PURPOSE

We report a case of unilateral acute iris transillumination (AIT) and iris sphincter paralysis in a 63-year-old male undergone uneventful phacoemulsification surgery with intracameral moxifloxacin (ICM).

CASE PRESENTATION

This is a case of AIT with no history of viral disease or use of systemic fluoroquinolone but an association with ICM after uneventful phacoemulsification. The clinical features of the affected eye are perfectly similar to what has been described in BAIT and hence we consider that unilateral AIT and BAIT share the same etiopathogenesis. At the end of the phacoemulsification, the patient received 0.15 ml of 5mg/ml moxifloxacin, which is notably higher than the dose that is commonly used for ICM. This may have caused the patient to develop BAIT-like syndrome after the ICM.

CONCLUSION

0.1 ml of 5mg/ml moxifloxacin or less should be used to reduce the risk of occurrences of this toxic effect caused by ICM.

摘要

目的

我们报告一例63岁男性患者,在接受了顺利的白内障超声乳化手术并眼内注射莫西沙星(ICM)后,出现单侧急性虹膜透照缺损(AIT)和虹膜括约肌麻痹。

病例介绍

这是一例AIT患者,无病毒病史或全身性氟喹诺酮类药物使用史,但在顺利的白内障超声乳化术后与ICM有关联。患眼的临床特征与BAIT中所描述的完全相似,因此我们认为单侧AIT和BAIT具有相同的发病机制。在白内障超声乳化手术结束时,患者接受了0.15毫升5毫克/毫升的莫西沙星,这明显高于ICM常用剂量。这可能导致患者在ICM后出现类似BAIT的综合征。

结论

应使用0.1毫升5毫克/毫升或更少的莫西沙星以降低由ICM引起的这种毒性作用的发生风险。

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