Department of Ophthalmology, University of Puerto Rico School of Medicine, Medical Sciences Campus, San Juan, Puerto Rico, USA.
Ocul Immunol Inflamm. 2024 Sep;32(7):1368-1373. doi: 10.1080/09273948.2023.2246543. Epub 2023 Aug 31.
To describe the clinical and demographic characteristics and associated factors leading to bilateral acute iris transillumination (BAIT) syndrome.
A retrospective review of patients with BAIT syndrome was performed.
Thirty-five patients with a diagnosis of BAIT were identified. The median age at presentation was 53 years; 80% of the patients were female. Twenty-six patients (74%) had recent histories of systemic antibiotic treatment. Of those with such a history, 24 patients (92%) had been receiving moxifloxacin. Two patients within our cohort were prescribed moxifloxacin prophylactically prior to a systemic surgical procedure and had no evidence of systemic illness or recent viral illness.
Our data support the notion that moxifloxacin might be associated with the onset of BAIT syndrome. Notably, within our cohort, two patients received moxifloxacin as surgical prophylaxis and subsequently developed BAIT syndrome. This could suggest a potential association between moxifloxacin and the onset of BAIT, though further studies are needed to confirm this finding.
描述导致双侧急性虹膜透照（BAIT）综合征的临床和人口统计学特征及相关因素。
对 BAIT 综合征患者进行回顾性分析。
共确定了 35 例 BAIT 诊断患者。发病时的中位年龄为 53 岁；80%的患者为女性。26 名患者（74%）有近期全身抗生素治疗史。在有此病史的患者中，24 名患者（92%）接受了莫西沙星治疗。我们的队列中有 2 名患者在全身手术前预防性使用了莫西沙星，且没有全身疾病或近期病毒感染的证据。
我们的数据支持莫西沙星可能与 BAIT 综合征的发病有关的观点。值得注意的是，在我们的队列中，有 2 名患者接受了莫西沙星作为手术预防用药，随后出现了 BAIT 综合征。这可能提示莫西沙星与 BAIT 的发病之间存在潜在关联，但需要进一步研究来证实这一发现。
