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双侧急性虹膜光透射(BAIT):一种可能与 COVID-19 和莫西沙星使用相关的罕见综合征。报告 2 例。

Bilateral Acute Iris Transillumination (BAIT): A Rare Syndrome Possibly Associated with COVID-19 and Moxifloxacin Use. A Report of 2 Cases.

机构信息

Department of Ophthalmology and Optometry, Sestre Milosrdnice University Hospital Center, Zagreb, Croatia.

出版信息

Semin Ophthalmol. 2023 Apr;38(3):312-315. doi: 10.1080/08820538.2023.2168491. Epub 2023 Jan 18.

DOI:10.1080/08820538.2023.2168491
PMID:36653737
Abstract

Bilateral acute iris transillumination (BAIT) is a rare clinical entity, presumed to be associated with preceding upper respiratory tract infection and/or use of certain antibiotics, marked by bilateral acute loss of iris pigment epithelium with pigment dispersion in the anterior chamber and trabecular meshwork, which can cause elevated intraocular pressure and glaucoma, and with iris transillumination and sphincter paralysis which lead to photophobia and blurry vision. We report the first two cases of BAIT in our center which both had a history of preceding COVID-19 (coronavirus disease 2019) and moxifloxacin use. With more awareness, ophthalmologists might diagnose more cases, and thus gain more information regarding the link between COVID-19 and BAIT, which might be underdiagnosed since it is rare or easily misdiagnosed as some more common diseases with similar features.

摘要

双侧急性虹膜光透射(BAIT)是一种罕见的临床病症,据推测与上呼吸道感染和/或使用某些抗生素有关,其特征为双侧急性虹膜色素上皮丧失伴前房和小梁网色素弥散,可导致眼内压升高和青光眼,并伴有虹膜光透射和括约肌麻痹,导致畏光和视力模糊。我们报告了首例 2 例 BAIT,均有 COVID-19(新型冠状病毒肺炎)和莫西沙星使用史。随着更多的认识,眼科医生可能会诊断出更多的病例,从而获得更多关于 COVID-19 与 BAIT 之间联系的信息,由于这种病症较为罕见或容易误诊为某些具有相似特征的更常见疾病,因此可能存在漏诊。

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