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基于普及医疗的动脉粥样硬化疾病筛查的最新进展

Recent Advances in Atherosclerotic Disease Screening Using Pervasive Healthcare.

作者信息

Luo Jingjing, Yan Zhengrong, Guo Shijie, Chen Wei

出版信息

IEEE Rev Biomed Eng. 2022;15:293-308. doi: 10.1109/RBME.2021.3081180. Epub 2022 Jan 20.

DOI:10.1109/RBME.2021.3081180
PMID:34003754
Abstract

Atherosclerosis screening helps the medical model transform from therapeutic medicine to preventive medicine by assessing degree of atherosclerosis prior to the occurrence of fatal vascular events. Pervasive screening emphasizes atherosclerotic monitoring with easy access, quick process, and advanced computing. In this work, we introduced five cutting-edge pervasive technologies including imaging photoplethysmography (iPPG), laser Doppler, radio frequency (RF), thermal imaging (TI), optical fiber sensing and piezoelectric sensor. IPPG measures physiological parameters by using video images that record the subtle skin color changes consistent with cardiac-synchronous blood volume changes in subcutaneous arteries and capillaries. Laser Doppler obtained the information on blood flow by analyzing the spectral components of backscattered light from the illuminated tissues' surface. RF is based on Doppler shift caused by the periodic movement of the chest wall induced by respiration and heartbeat. TI measures vital signs by detecting electromagnetic radiation emitted by blood flow. The working principle of optical fiber sensor is to detect the change of light properties caused by the interaction between the measured physiological parameter and the entering light. Piezoelectric sensors are based on the piezoelectric effect of dielectrics. All these pervasive technologies are noninvasive, mobile, and can detect physiological parameters related to atherosclerosis screening.

摘要

动脉粥样硬化筛查通过在致命性血管事件发生之前评估动脉粥样硬化程度,有助于医学模式从治疗医学向预防医学转变。普及型筛查强调通过易于获取、流程快速且具备先进计算能力的方式进行动脉粥样硬化监测。在这项工作中,我们引入了五种前沿的普及型技术,包括成像光电容积脉搏波描记法(iPPG)、激光多普勒、射频(RF)、热成像(TI)、光纤传感和压电传感器。iPPG通过使用视频图像来测量生理参数,这些图像记录了与皮下动脉和毛细血管中心脏同步血容量变化一致的细微皮肤颜色变化。激光多普勒通过分析来自被照亮组织表面的背向散射光的光谱成分来获取血流信息。射频基于呼吸和心跳引起的胸壁周期性运动所导致的多普勒频移。热成像通过检测血流发射的电磁辐射来测量生命体征。光纤传感器的工作原理是检测由被测生理参数与入射光之间的相互作用引起的光特性变化。压电传感器基于电介质的压电效应。所有这些普及型技术都是非侵入性的、可移动的,并且能够检测与动脉粥样硬化筛查相关的生理参数。

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Recent Advances in Atherosclerotic Disease Screening Using Pervasive Healthcare.基于普及医疗的动脉粥样硬化疾病筛查的最新进展
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