Troshina E A, Platonova N M, Panfilova E A
Endocrinology Research Centre.
Probl Endokrinol (Mosk). 2021 Apr 9;67(2):10-19. doi: 10.14341/probl12433.
The level of iodine consumption by the population largery determines the spectrum of thyroid pathology. To date, in the Russian Federation, iodine-deficiency disorders (IDD) occupy a leading position in the structure of all thyroid diseases. Chronic ID leads to adverse health consequences and significant economic costs for their elimination on a national scale. However, the spectrum of thyroid pathology is not limited to the problem of ID, and the study of other thyroid diseases is also of interest.
to assess the dynamics of prevalence and incidence of IDD and other thyroid diseases in the entire population of the RF for the period 2009-2018, using official state statistics.
the main epidemiological indicators (incidence and prevalence) of thyroid diseases in the entire population of the RF were analyzed using official state statistics. The analyzed period is 2009-2018. There was no medical intervention. To assess the dynamics of prevalence and incidence, a linear regression models were constructed, the slope of the trend line was calculated.
the data were analyzed in accordance with the structure of diseases presented in the statistical reporting: goiter, thyroiditis, hypothyroidism, thyrotoxicosis, congenital iodine deficiency syndrome. For the ten-year period 2009-2018 there is a statistically significant increase in the prevalence of various forms of goiter, thyrotoxicosis, congenital iodine deficiency syndrome in the entire population of the Russian Federation. During the observation period, an increase in the incidence of thyrotoxicosis was revealed. With regard to the incidence of congenital iodine deficiency syndrome, only an upward trend was revealed. Despite the fact that during the observation period the number of new cases of various forms of goiter decreased, the prevalence of goiter among the population of the Russian Federation remains high: 1.2% of the population by January 1, 2019. with the growth of autoimmune pathology, improvement of the level of diagnosis, and also, in some cases, with overdiagnosis (for example, when diagnosing autoimmune thyroiditis in individuals with asymptomatic carriage of antithyroid antibodies). The current approaches to iodine prophylaxis are not effective enough.
the results of the analysis indicate mainly an increase in the high prevalence of thyroid pathology among the population of the RF against the background of regional events. The problem of ID remains unresolved, which dictates the need to introduce universal mandatory salt iodization in the territory of the RF.
人群的碘摄入量水平在很大程度上决定了甲状腺疾病的谱型。迄今为止,在俄罗斯联邦,碘缺乏病(IDD)在所有甲状腺疾病的结构中占据主导地位。慢性碘缺乏会导致不良健康后果,并且在全国范围内消除碘缺乏病需要巨大的经济成本。然而,甲状腺疾病谱并不局限于碘缺乏问题,对其他甲状腺疾病的研究也具有重要意义。
利用官方国家统计数据,评估2009 - 2018年期间俄罗斯联邦全体人口中碘缺乏病和其他甲状腺疾病的患病率及发病率动态变化。
使用官方国家统计数据对俄罗斯联邦全体人口中甲状腺疾病的主要流行病学指标(发病率和患病率)进行分析。分析时间段为2009 - 2018年。未进行医学干预。为评估患病率和发病率的动态变化,构建了线性回归模型,并计算了趋势线的斜率。
根据统计报告中呈现的疾病结构对数据进行分析:甲状腺肿、甲状腺炎、甲状腺功能减退、甲状腺毒症、先天性碘缺乏综合征。在2009 - 2018年的十年间,俄罗斯联邦全体人口中各种形式的甲状腺肿、甲状腺毒症、先天性碘缺乏综合征的患病率在统计学上有显著增加。在观察期内,发现甲状腺毒症的发病率有所上升。关于先天性碘缺乏综合征的发病率,仅呈现出上升趋势。尽管在观察期内各种形式甲状腺肿的新发病例数量有所下降,但俄罗斯联邦人口中甲状腺肿的患病率仍然很高:截至2019年1月1日,占人口的1.2%。随着自身免疫性疾病的增加、诊断水平的提高,以及在某些情况下的过度诊断(例如,在抗甲状腺抗体无症状携带者中诊断自身免疫性甲状腺炎),当前的碘预防方法不够有效。
分析结果表明,在区域事件的背景下,俄罗斯联邦人口中甲状腺疾病的高患病率主要呈上升趋势。碘缺乏问题仍未得到解决,这表明有必要在俄罗斯联邦领土上推行普遍强制食盐加碘。