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[碘缺乏病:布良斯克地区问题的现状]

[Iodine Deficiency Disorders: Current State of the Problem in the Bryansk Region].

作者信息

Troshina E A, Makolina N P, Senyushkina E S, Nikankina L V, Malysheva N M, Fetisova A V

机构信息

Endocrinology Research Centre.

Department of Health of the Bryansk Region.

出版信息

Probl Endokrinol (Mosk). 2021 Aug 3;67(4):84-93. doi: 10.14341/probl12793.

Abstract

BACKGROUND

The Bryansk region is one of the regions of the Russian Federation most affected by the accident at the Chernobyl nuclear power plant on April 26, 1986.In the conditions of a chronic uncompensated deficiency of iodine in the diet in the first months after the accident, an active seizure of radioactive iodine by the thyroid tissue took place, which inevitably resulted in an increase in thyroid diseases from the population in the future. The article presents the results of a control and epidemiological study carried out in May 2021 by specialists of the National Medical Research Center of Endocrinology of the Ministry of Health of Russia, aimed at assessing the current state of iodine provision in the population of the Bryansk region.

AIM

Assessment of iodine supply of the population of the Bryansk region.

MATERIALS AND METHODS

The research was carried out in secondary schools of three districts of the Bryansk region (Bryansk, Novozybkov and Klintsy).The study included 337 schoolchildren of pre-pubertal age (8-10 years), all children underwent: measurement of height and weight immediately before the doctor's examination, which included palpation of the thyroid gland (thyroid gland); Thyroid ultrasound using a portable device LOGIQe (China) with a multi-frequency linear transducer 10-15 MHz; determination of iodine concentration in single portions of urine. A qualitative study for the presence of potassium iodate in samples of table salt (n = 344) obtained from households and school canteens was carried out on the spot using the express method.

RESULTS

According to the results of a survey of 337 pre-pubertal children, the median urinary iodine concentration (mCIM) is 98.3 μg / L (range from 91.5 to 111.5 μg / L, the proportion of urine samples with a reduced iodine concentration was 50.1%). According to the ultrasound of the thyroid gland, 17% of the examined children had diffuse goiter, the frequency of which varied from 9.4 to 29% in the areas of study. The share of iodized salt consumed in the families of schoolchildren in the study areas was 17.8% (values range from 15.6 to 19%), which indicates an extremely low level of iodized salt consumption by the population. All salt used for cooking in school canteen areas of the study was iodized, which confirms compliance with the requirements of SanPiN 2.4.5.2409-08.

CONCLUSION

Despite the active implementation in the Bryansk region of various preventive programs of IDD and social activities to promote the use of iodized salt, in the absence of mass prevention with the help of iodized salt to date, their unsatisfactory results should be noted.

摘要

背景

布良斯克地区是俄罗斯联邦受1986年4月26日切尔诺贝利核电站事故影响最严重的地区之一。在事故后的头几个月,饮食中长期碘摄入不足的情况下,甲状腺组织积极摄取放射性碘,这不可避免地导致未来该地区居民甲状腺疾病增多。本文介绍了俄罗斯卫生部国家内分泌医学研究中心的专家于2021年5月进行的一项对照和流行病学研究结果,旨在评估布良斯克地区居民当前的碘供应状况。

目的

评估布良斯克地区居民的碘供应情况。

材料与方法

研究在布良斯克地区的三个区(布良斯克、新兹韦科夫和克林齐)的中学进行。研究包括337名青春期前儿童(8 - 10岁),所有儿童均接受:在医生检查前立即测量身高和体重,医生检查包括触诊甲状腺;使用配有10 - 15 MHz多频率线性换能器的便携式LOGIQe设备(中国)进行甲状腺超声检查;测定单次尿样中的碘浓度。使用快速方法对从家庭和学校食堂获取的食盐样本(n = 344)中碘酸钾的存在情况进行定性研究。

结果

根据对337名青春期前儿童的调查结果,尿碘中位数浓度(mCIM)为98.3 μg/L(范围为91.5至111.5 μg/L,碘浓度降低的尿样比例为50.1%)。根据甲状腺超声检查,17%的受检儿童患有弥漫性甲状腺肿,其发生率在研究区域内从9.4%至29%不等。研究区域内学童家庭食用加碘盐的比例为17.8%(值范围为15.6%至19%),这表明居民加碘盐消费水平极低。研究区域学校食堂烹饪所用的所有盐均为加碘盐,这证实符合卫生规范2.4.5.2409 - 08的要求。

结论

尽管布良斯克地区积极实施了各种碘缺乏病预防计划和促进使用加碘盐的社会活动,但迄今为止,在没有借助加碘盐进行大规模预防的情况下,应注意到其效果并不理想。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fe1/9753831/cfdc523e3023/problendo-67-12793-g001.jpg

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