Roman Jan, Vávra Petr, Vávrová Michaela, Židlík Vladimír, Pelikán Anton
Faculty of Medicine, University of Ostrava, Ostrava, The Czech Republic.
Department of Surgery, University Hospital Ostrava, Ostrava, The Czech Republic.
Acta Chir Belg. 2023 Feb;123(1):90-93. doi: 10.1080/00015458.2021.1932180. Epub 2021 Jun 2.
Solitary fibrous tumour of the liver is a rare mesenchymal tumour, occurring usually in women and with various symptomatology. The symptoms mostly result from pressure of the tumour mass on surrounding organs. Due to unknown biological behaviour and gradual increase of tumour volume, surgical resection is mostly the preferred treatment option.
A 75-year-old woman with a history of endometrial cancer, presenting with an incidental finding of a liver mass, initially considered of infectious origin (either echinococcosis or cysticercosis). Further diagnostics did not clarify the aetiology, a surgical revision was rejected at the time. The subsequent follow-up was interrupted by the development of symptoms of gastrointestinal and renal obstruction, which led to a complete surgical removal of the tumour, sized 30 × 25 × 20 cm. A histopathological examination showed a and positivity, leading to a diagnosis of a giant solitary fibrous tumour of the liver. The patient recovered well, without any signs of recurrence.
The solitary fibrous tumour of the liver is a rare, often incidental finding. It is considered benign, but malignant growth was also reported. A gradual growth mostly results in pressure on other organs. A surgical resection is the treatment of choice. Transarterial embolization is another treatment possibility. Due to indeterminate malignant potential a regular follow-up is necessary, including tumour markers and imaging methods.
肝脏孤立性纤维瘤是一种罕见的间叶组织肿瘤，通常发生于女性，具有多种症状表现。症状大多源于肿瘤肿块对周围器官的压迫。由于其生物学行为不明且肿瘤体积逐渐增大，手术切除大多是首选的治疗方案。
一名75岁有子宫内膜癌病史的女性，偶然发现肝脏肿块，最初考虑为感染性病因（棘球蚴病或囊尾蚴病）。进一步诊断未明确病因，当时拒绝了手术探查。随后的随访因出现胃肠道和肾脏梗阻症状而中断，这导致对大小为30×25×20 cm的肿瘤进行了完整的手术切除。组织病理学检查显示[此处原文缺失相关内容]呈阳性，从而诊断为巨大肝脏孤立性纤维瘤。患者恢复良好，无任何复发迹象。
肝脏孤立性纤维瘤较为罕见，常为偶然发现。它被认为是良性的，但也有恶性生长的报道。其逐渐生长大多会导致对其他器官的压迫。手术切除是首选治疗方法。经动脉栓塞是另一种治疗选择。由于恶性潜能不确定，需要定期随访，包括肿瘤标志物和影像学检查方法。
