Xie Guang-Yuan, Zhu Huan-Bing, Jin Yun, Li Bai-Zhou, Yu Yuan-Quan, Li Jiang-Tao
Department of Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China.
Department of Pathology, The Second Affiliated Hospital, Zhejiang University School of Medicine, HangZhou 310000, Zhejiang Province, China.
World J Clin Cases. 2022 Jul 16;10(20):7097-7104. doi: 10.12998/wjcc.v10.i20.7097.
Hepatic solitary fibrous tumor (SFT) is a rare neoplasm. Up to now, only 90 cases have been reported in the English language literature. This report describes a case of SFT of the liver misdiagnosed as hepatocellular carcinoma.
A 42-year-old male had a two-year history of a gradually enlarging intrahepatic nodule. The preoperative imaging revealed a mass with a size of 2.7 cm × 2.3 cm located in the segment IV of the liver. The patient was subjected to the resection of the segment IV, such as the medial segment of the left lobe of the liver. The histological examination of the mass showed various spindled cells irregularly arranged in the stroma. The immunohistochemistry of this mass revealed a positive staining for CD34 and STAT6. The history of intracranial tumor and postoperative pathological results led to the diagnosis of SFT of the liver (SFTL) due to a metastasis from the brain.
SFTL is an uncommon mesenchymal neoplasm that can be easily overlooked or misdiagnosed. The best treatment choice is the complete surgical resection of the mass. A regular follow-up after the surgery should be performed due to the poor prognosis of metastatic or recurrent SFT.
肝脏孤立性纤维瘤（SFT）是一种罕见的肿瘤。截至目前，英文文献中仅报道了90例。本报告描述了一例被误诊为肝细胞癌的肝脏SFT病例。
一名42岁男性有一个肝内结节逐渐增大两年的病史。术前影像学检查显示一个大小为2.7 cm×2.3 cm的肿块位于肝IV段。患者接受了IV段切除，即肝左叶内侧段切除。肿块的组织学检查显示在间质中有各种不规则排列的梭形细胞。该肿块的免疫组化显示CD34和STAT6呈阳性染色。颅内肿瘤病史和术后病理结果导致诊断为肝SFT（SFTL），系脑转移所致。
SFTL是一种罕见的间叶性肿瘤，容易被忽视或误诊。最佳治疗选择是完整切除肿块。由于转移性或复发性SFT预后较差，术后应定期随访。
