Sherrard D J, Walker J V, Boykin J L
Department of Medicine, Seattle Veterans Administration Medical Center, WA 98108.
Am J Kidney Dis. 1988 Aug;12(2):126-30. doi: 10.1016/s0272-6386(88)80007-6.
Five patients with chronic renal failure, complicated by bone aluminum toxicity, were treated with deferoxamine (DFO). This treatment appeared to precipitate dialysis dementia, which was fatal in three patients. In two patients, continuous treatment with lower doses of DFO was possible. The development of dialysis dementia in chronic renal failure patients with very high serum aluminum levels may be a complication of DFO treatment.
五名患有慢性肾衰竭并伴有骨铝中毒的患者接受了去铁胺（DFO）治疗。这种治疗似乎引发了透析性痴呆，其中三名患者因此死亡。另外两名患者能够持续接受较低剂量的DFO治疗。血清铝水平极高的慢性肾衰竭患者出现透析性痴呆可能是DFO治疗的一种并发症。
