Department of Pediatrics, Brooke Army Medical Center, San Antonio, TX, USA.
Department of Pediatrics, Uniformed Services University of Health Sciences, Bethesda, MD, USA.
J Perinatol. 2021 Aug;41(8):2088-2094. doi: 10.1038/s41372-021-01069-8. Epub 2021 May 18.
To study the effects of a supplementation-based hypoglycemia guideline including donor (DM) on NICU admission, exclusive breastfeeding, and blood glucose concentrations in infants at-risk for neonatal hypoglycemia (NH).
We integrated DM, feeding supplementation, and reduced frequency of blood glucose testing into an NH bundle for term and late-preterm newborns. We then examined NICU admission rates and rates of exclusive breastfeeding at discharge.
NICU admission rates were reduced to 6% (-10%). Exclusive breastfeeding rates increased to 55% (+22%). Median cost of DM utilization was $13.73 per patient with an average volume of 50.8 ml/infant. DM supplementation resulted in similar times to last hypoglycemic episode and greater increases in blood glucose compared to expressed breast milk or breastfeeding alone (+9.6 mg/dL, p < 0.05).
A supplementation-based hypoglycemia guideline including donor milk may be an effective way to reduce NICU admissions for asymptomatic hypoglycemia and support mothers in achieving breastfeeding goals.
研究包括捐赠者（DM）在内的基于补充的低血糖指南对新生儿重症监护病房（NICU）入院、纯母乳喂养以及有新生儿低血糖（NH）风险的婴儿血糖浓度的影响。
我们将 DM、喂养补充和减少血糖检测频率整合到针对足月和晚期早产儿的 NH 套餐中。然后，我们检查了 NICU 入院率和出院时纯母乳喂养率。
NICU 入院率降低至 6%（-10%）。纯母乳喂养率增加到 55%（+22%）。每位患者的 DM 使用成本中位数为 13.73 美元，平均用量为 50.8 毫升/婴儿。与单独使用母乳或母乳喂养相比，DM 补充剂可使最后一次低血糖发作的时间相似，并使血糖升高更多（+9.6mg/dL，p<0.05）。
包括捐赠奶在内的基于补充的低血糖指南可能是减少无症状低血糖导致的 NICU 入院和支持母亲实现母乳喂养目标的有效方法。
