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Bone density and cortical thickness in nutritional vitamin D deficiency: effect of secondary hyperparathyroidism.

作者信息

Fonseca V, Agnew J E, Nag D, Dandona P

机构信息

Department of Chemical Pathology, Royal Free Hospital and School of Medicine, London, UK.

出版信息

Ann Clin Biochem. 1988 May;25 ( Pt 3):271-4. doi: 10.1177/000456328802500314.

DOI:10.1177/000456328802500314
PMID:3400984
Abstract

Measurements of bone mineral index, mean metacarpal cortical thickness, plasma calcium, alkaline phosphatase and serum 25-hydroxyvitamin D and parathyroid hormone concentrations were carried out in 39 Asian vegetarian patients with hypovitaminosis D. It was concluded that PTH is probably the major determinant of osteopenia in patients with osteomalacia and secondary hyperparathyroidism; and that the presence of secondary hyperparathyroidism in association with hypovitaminosis D should be an absolute indication for vitamin D supplementation even in asymptomatic patients.

摘要

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