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在刚果共和国的蝙蝠样本中检测到以前未知的弹状病毒序列。

Sequences of Previously Unknown Rhabdoviruses Detected in Bat Samples from the Republic of the Congo.

机构信息

Wildlife Conservation Society, Bronx, New York, USA.

United States Fish and Wildlife Service, Bailey's Crossroads, Virginia, USA.

出版信息

Vector Borne Zoonotic Dis. 2021 Jul;21(7):552-555. doi: 10.1089/vbz.2020.2736. Epub 2021 May 19.

DOI:10.1089/vbz.2020.2736
PMID:34010076
Abstract

The family contains diverse viruses, including vector-borne and nonvector-borne viruses, some that are human pathogens, including rabies virus and also nonpathogenic viruses. Bats, which are a known reservoir of viruses with zoonotic potential including coronaviruses, also carry multiple rhabdoviruses such as but not limited to lyssaviruses. We collected samples from 193 insectivorous and frugivorous bats in the Republic of the Congo and tested them for rhabdovirus RNA. Four samples were found positive for viral RNA representing sequences of four different, not previously described rhabdoviruses. Although phylogenetic and taxonomic placement of the novel sequences is uncertain, similarities with previously detected rhabdovirus sequences in bats suggest that these could represent vertebrate viruses. Considering the pathogenic risks some rhabdoviruses pose for humans, these results highlight the need for more research and surveillance regarding rhabdoviruses and bats.

摘要

该家族包含多种病毒,包括媒介传播和非媒介传播病毒,其中一些是人类病原体,包括狂犬病病毒和非致病性病毒。蝙蝠是具有人畜共患潜力的病毒的已知宿主,包括冠状病毒,也携带多种弹状病毒,如但不限于狂犬病病毒。我们从刚果共和国的 193 种食虫和食果蝙蝠中采集样本,并检测它们的弹状病毒 RNA。有 4 个样本的病毒 RNA 呈阳性,代表 4 种不同的、以前未描述的弹状病毒序列。尽管新型序列的系统发育和分类位置不确定,但与蝙蝠中以前检测到的弹状病毒序列的相似性表明,这些可能代表脊椎动物病毒。考虑到一些弹状病毒对人类的致病风险,这些结果强调需要对弹状病毒和蝙蝠进行更多的研究和监测。

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