阿扎丙宗和8-羟基阿扎丙宗对黄嘌呤氧化酶的体外抑制作用。
In vitro inhibition of xanthine oxidase by azapropazone and 8-hydroxy-azapropazone.
作者信息
Jahn U, Thiele K
机构信息
Biology and Research Department, Siegfried Ltd., Zofingen, Switzerland.
出版信息
Arzneimittelforschung. 1988 Apr;38(4):507-8.
PMID:3401265
Abstract
It has been demonstrated that the nonsteroidal antiinflammatory agent azapropazone (Prolixan) as well as its principal 8-hydroxy-metabolite have distinct xanthine oxidase inhibitory activity. The pharmacological spectrum of this compound has thus shown an interesting extension.
摘要
已证实非甾体抗炎药阿扎丙宗（Prolixan）及其主要的8-羟基代谢物具有明显的黄嘌呤氧化酶抑制活性。因此，该化合物的药理谱显示出有趣的扩展。
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