Caetano Inês, Amorim Liliana, Soares José Miguel, Ferreira Sónia, Coelho Ana, Reis Joana, Santos Nadine Correia, Moreira Pedro Silva, Marques Paulo, Magalhães Ricardo, Esteves Madalena, Picó-Pérez Maria, Sousa Nuno
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057, Braga, Portugal.
ICVS/3B's, PT Government Associate Laboratory, 4710-057, Braga/Guimarães, Portugal.
Neurobiol Stress. 2021 May 1;14:100334. doi: 10.1016/j.ynstr.2021.100334. eCollection 2021 May.
Stress is inevitably linked to life. It has many and complex facets. Notably, perception of stressful stimuli is an important factor when mounting stress responses and measuring its impact. Indeed, moved by the increasing number of stress-triggered pathologies, several groups drew on advanced neuroimaging techniques to explore stress effects on the brain. From that, several regions and circuits have been linked to stress, and a comprehensive integration of the distinct findings applied to common individuals is being pursued, but with conflicting results. Herein, we performed a volumetric regression analysis using participants' perceived stress as a variable of interest. Data shows that increased levels of perceived stress positively associate with the right amygdala and anterior hippocampal volumes.
压力与生活不可避免地联系在一起。它具有许多复杂的方面。值得注意的是,在产生应激反应并衡量其影响时,对应激刺激的感知是一个重要因素。事实上,由于应激引发的病症数量不断增加,一些研究团队利用先进的神经成像技术来探索压力对大脑的影响。由此,几个脑区和神经回路已被证实与压力有关,目前正在努力将这些不同的研究结果综合应用于普通人,但结果相互矛盾。在此,我们以参与者感知到的压力作为感兴趣的变量进行了体积回归分析。数据显示,感知到的压力水平升高与右侧杏仁核和前海马体体积呈正相关。