Moon Ashley S, Dorigo Oliver
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Stanford School of Medicine, Stanford Cancer Institute, Stanford, CA, USA.
Gynecol Oncol Rep. 2021 Apr 30;36:100770. doi: 10.1016/j.gore.2021.100770. eCollection 2021 May.
•Recurrent, non-resectable ovarian granulosa cell tumor has no standard treatment.•Estrogen/progesterone receptor signaling regulates granulosa cell tumor growth.•Granulosa cell tumor responds well to alternating megestrol and tamoxifen therapy.
•复发性、不可切除的卵巢颗粒细胞瘤尚无标准治疗方法。
•雌激素/孕激素受体信号传导调节颗粒细胞瘤的生长。
•颗粒细胞瘤对甲地孕酮和他莫昔芬交替治疗反应良好。