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Understanding Retinal Vasculitis Associated with Brolucizumab: Complex Pathophysiology or Occam's Razor?

作者信息

Sharma Ashish, Kumar Nilesh, Parachuri Nikulaa, Singh Sonali, Bandello Francesco, Regillo Carl D, Boyer David, Nguyen Quan Dong

机构信息

Lotus Eye Hospital and Institute, Coimbatore, India.

Ocular Pathologist, Madhavi Netralaya, Ara, India.

出版信息

Ocul Immunol Inflamm. 2022 Aug;30(6):1508-1510. doi: 10.1080/09273948.2021.1897628. Epub 2021 May 20.

Abstract
摘要

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Brolucizumab-related retinal vasculitis with exacerbation following ranibizumab retreatment: A clinicopathologic case study.
Am J Ophthalmol Case Rep. 2020 Nov 10;20:100989. doi: 10.1016/j.ajoc.2020.100989. eCollection 2020 Dec.
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Ophthalmology. 2021 Jul;128(7):1050-1059. doi: 10.1016/j.ophtha.2020.11.011. Epub 2020 Nov 15.
3
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Ophthalmol Retina. 2021 Jun;5(6):519-527. doi: 10.1016/j.oret.2020.09.020. Epub 2020 Sep 29.
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Occlusive Retinal Vasculitis Following Intravitreal Brolucizumab.
J Vitreoretin Dis. 2020 Jul;4(4):269-279. doi: 10.1177/2474126420930863. Epub 2020 Jul 1.
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Retinal Vasculitis and Intraocular Inflammation after Intravitreal Injection of Brolucizumab.
Ophthalmology. 2020 Oct;127(10):1345-1359. doi: 10.1016/j.ophtha.2020.04.017. Epub 2020 Apr 25.
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Severe vision loss secondary to retinal arteriolar occlusions after multiple intravitreal brolucizumab administrations.
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Retinal arterial occlusive vasculitis following intravitreal brolucizumab administration.
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