School of Chemical Engineering and Technology, State Key Laboratory of Chemical Engineering, Tianjin University, Tianjin 300072, P.R. China.
Tianjin Key Laboratory of Membrane Science and Desalination Technology, Tianjin University, Tianjin 300072, P.R. China.
Nano Lett. 2021 Aug 11;21(15):6406-6415. doi: 10.1021/acs.nanolett.1c00697. Epub 2021 May 20.
Self-assembled peptide materials with sequence-encoded properties have attracted great interest. Despite their intrinsic chirality, the generation of circularly polarized luminescence (CPL) based on the self-assembly of simple peptides has been rarely reported. Here, we report the self-assembly of peptides into hierarchical helical arrays (HHAs) with controlled supramolecular handedness. The HHAs can emit full-color CPL signals after the incorporation of various achiral fluorescent molecules, and the value is 40 times higher than that of the CPL signal from the solutions. By simply changing the amino acid sequence of the peptides, CPL signals with opposite handedness can be generated within the HHAs. The peptide HHAs can provide hydrophobic pockets to accommodate the fluorescent molecules with helical arrangement through strong aromatic stacking interactions, which are responsible for the CPL signals. This work provides a pathway to construct highly ordered chiral materials, which have broad applications in the chiroptical field.
具有序列编码特性的自组装肽材料引起了极大的关注。尽管它们具有内在的手性，但基于简单肽自组装产生圆偏振发光（CPL）的报道却很少。在这里，我们报告了肽组装成具有受控超分子手性的分级螺旋阵列（HHAs）。在掺入各种手性荧光分子后，HHAs 可以发射全彩 CPL 信号，其值比溶液中的 CPL 信号高 40 倍。通过简单地改变肽的氨基酸序列，可以在 HHAs 中产生具有相反手性的 CPL 信号。肽 HHAs 可以通过强芳香堆积相互作用提供容纳具有螺旋排列的荧光分子的疏水性口袋，这是 CPL 信号的来源。这项工作为构建高度有序的手性材料提供了一种途径，在手性光学领域有广泛的应用。
