在肿瘤性间皮细胞条件培养基存在的情况下，正常和肿瘤性大鼠胸膜间皮细胞的生长
Growth of normal and neoplastic rat pleural mesothelial cells in the presence of conditioned medium from neoplastic mesothelial cells.
作者信息
Van der Meeren A, Levy F, Bignon J, Jaurand M C
机构信息
Equipe Pathologie Cellulaire de l'Environnement, INSERM U 139, CHU Henri Mondor, Créteil, France.
出版信息
Biol Cell. 1988;62(3):293-6. doi: 10.1016/0248-4900(88)90025-1.
PMID:3401620
Abstract
Several transformed cells have been demonstrated to secrete growth factors. We studied the effect of conditioned medium from neoplastic rat pleural mesothelial cells on normal and neoplastic mesothelial cell growth. The results showed that the concentrated conditioned medium stimulated neoplastic mesothelial cell growth but inhibited reversibly normal mesothelial cell growth.
摘要
已证实几种转化细胞能分泌生长因子。我们研究了来自肿瘤大鼠胸膜间皮细胞的条件培养基对正常和肿瘤性间皮细胞生长的影响。结果表明，浓缩的条件培养基刺激肿瘤性间皮细胞生长，但可逆地抑制正常间皮细胞生长。
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