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一项评估在体外受精过程中使用基于网络的应用程序来管理药物的随机对照试验。

A randomized controlled trial to evaluate the use of a web-based application to manage medications during in vitro fertilization.

机构信息

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Washington University in St. Louis, St. Louis, Missouri.

Department of Learning Health Sciences, Michigan Medicine, Ann Arbor, Michigan; Department of Obstetrics and Gynecology, Michigan Medicine, Ann Arbor, Michigan.

出版信息

Fertil Steril. 2021 Sep;116(3):793-800. doi: 10.1016/j.fertnstert.2021.04.022. Epub 2021 May 18.

DOI:10.1016/j.fertnstert.2021.04.022
PMID:34016436
Abstract

OBJECTIVE

To evaluate the use of a web-based application that assists in medication management during in vitro fertilization (IVF) treatment.

DESIGN

Multicenter randomized controlled trial.

SETTING

University hospitals.

PATIENT(S): Women undergoing IVF.

INTERVENTION(S): Subjects were recruited to assess quality of life during IVF and were randomly assigned to use either the OnTrack application to assist with medication management or conventional medication management. Surveys were administered at four time points.

MAIN OUTCOME MEASURE(S): Medication surplus, incidence of medication errors, amount of patient-initiated communication, and patient satisfaction.

RESULT(S): A total of 153 women participated. The average number of portal messages and telephone calls was similar between groups. Twelve patients in the control group (12/69, 17.4%) and 8 patients in the case group (8/72, 11.1%) made medication errors. There were similar amounts of medication surplus in the two groups. The estimated cost of medication waste was $2,578 ± $2,056 in the control group and $2,554 ± $1,855 in the case group. Patient satisfaction was similar between the two groups.

CONCLUSION(S): Use of a web-based application did not decrease medication errors, medication surplus, or patient-initiated messages. Many patients had a medication surplus, which can be an area of cost reduction during IVF.

CLINICAL TRIAL REGISTRATION NUMBER

Clinicaltrials.gov NCT03383848.

摘要

目的

评估一款基于网络的应用程序在体外受精(IVF)治疗中辅助药物管理的使用效果。

设计

多中心随机对照试验。

设置

大学医院。

患者

接受 IVF 的女性。

干预措施

招募受试者评估 IVF 期间的生活质量,并随机分配使用 OnTrack 应用程序辅助药物管理或常规药物管理。在四个时间点进行调查。

主要观察指标

药物过剩、药物错误发生率、患者主动沟通的次数和患者满意度。

结果

共有 153 名女性参与。两组之间的门户消息和电话数量平均相似。对照组中有 12 名患者(12/69,17.4%)和病例组中有 8 名患者(8/72,11.1%)发生了药物错误。两组的药物过剩量相似。对照组的药物浪费估计成本为 2578 美元±2056 美元,病例组为 2554 美元±1855 美元。两组患者满意度相似。

结论

使用基于网络的应用程序并没有降低药物错误、药物过剩或患者主动发起的信息数量。许多患者存在药物过剩,这是 IVF 期间降低成本的一个领域。

临床试验注册号

Clinicaltrials.gov NCT03383848。

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