Wang Jing, Li Peifen, Zhang Peijie, Du Qing
Department of Paediatrics, Ningbo Yinzhou District Second Hospital Ningbo 315100, Zhejiang Province, China.
Wound Ostomy Clinic, Ningbo Yinzhou District Second Hospital Ningbo 315100, Zhejiang Province, China.
Am J Transl Res. 2021 Apr 15;13(4):3443-3450. eCollection 2021.
To explore the application effect of detailed nursing intervention in neonatal septicemia.
Altogether 60 neonates of neonatal septicemia admitted to our hospital from November 2019 to October 2020 were selected as the research participants, and all the children have received routine treatment, among which 30 neonates received routine nursing intervention as the regular group, and the remaining 30 received detailed nursing intervention as the detail group. The clinical effects, improvement of clinical symptoms, length of stay, and guardian satisfaction were compared, and the levels of serum inflammatory factors (TNF-α, IL-6 and IL-17) and immune function indicators (CD4+, CD8+) before and after nursing intervention were detected.
The total effective rate in the detail group was higher than that in the regular group (P < 0.05). Compared with the regular group, the temperature stabilization time, blood culture turning negative time, improvement time of milk rejection and hospital stay in the detail group were significantly shortened (P < 0.05). The guardian satisfaction score in the detail group was higher than that in the regular group (P < 0.05). After nursing, the levels of TNF-α, IL-6 and IL-17 decreased in both groups, and the levels of these three in the detail group were lower than those in the regular group (P < 0.05). After nursing, CD4+/CD8+ of children in both groups increased, and CD4+/CD8+ in the detail group and regular group were higher than those in the regular group (P < 0.05).
The adoption of detailed nursing modes in the treatment of neonatal septicemia can further improve the treatment effect, shorten the hospital stay and the improvement time of clinical symptoms, reduce the incidence of complications, improve the nursing satisfaction of guardians, reduce the inflammation of the body and improve the immune function of the body.
探讨精细化护理干预在新生儿败血症中的应用效果。
选取2019年11月至2020年10月我院收治的60例新生儿败血症患儿作为研究对象，所有患儿均接受常规治疗，其中30例新生儿接受常规护理干预作为常规组，其余30例接受精细化护理干预作为精细化组。比较两组的临床疗效、临床症状改善情况、住院时间及监护人满意度，并检测护理干预前后血清炎症因子（TNF-α、IL-6和IL-17）水平及免疫功能指标（CD4+、CD8+）。
精细化组总有效率高于常规组（P<0.05）。与常规组相比，精细化组体温稳定时间、血培养转阴时间、拒乳改善时间及住院时间均明显缩短（P<0.05）。精细化组监护人满意度评分高于常规组（P<0.05）。护理后，两组TNF-α、IL-6和IL-17水平均下降，且精细化组这三项水平低于常规组（P<0.05）。护理后，两组患儿CD4+/CD8+均升高，且精细化组高于常规组（P<0.05）。
在新生儿败血症治疗中采用精细化护理模式可进一步提高治疗效果，缩短住院时间及临床症状改善时间，降低并发症发生率，提高监护人护理满意度，减轻机体炎症反应，提高机体免疫功能。
