Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Department of Expanded Program on Immunization, Lu'an Municipal Center for Disease Control and Prevention, Lu'an, Anhui, China.
Hum Vaccin Immunother. 2021 Sep 2;17(9):3137-3144. doi: 10.1080/21645515.2021.1904759. Epub 2021 May 21.
The school entry vaccination record check strategy (SECS) is an appropriate opportunity to recommend vaccines for students to improve vaccination coverage (VC). However, it is only utilized for providing necessary catch-up vaccination for students who are missing the Expanded Program on Immunization (EPI) vaccines in China. We aimed to address that gap and quantify the relationship between the SECS policy and the increase of coverage in varicella vaccine (VarV).
We employed a pretest and posttest quasi-experimental design to examine the effect of the upgraded SECS policy on the change of VarV coverage in newly enrolled students in Lu'an, 2019-2020.
Eight hundred participants were randomly divided into the control group (C group, 31.8%), the telephone-based intervention group (T group, 31.2%), and the written notification intervention group (W group, 37.0%). Totally, 84 students received VarV during the study period, with a VC of 10.5%. The possibility of vaccination in the T group (RR = 4.9, 95% CI:2.2-10.9) and W group (RR = 5.2, 95% CI:2.4-11.5) was significantly higher than that in the C group (< .001).
Our study demonstrates that the upgraded SECS produce a positive effect on improving the VC of VarV. This nudge strategy may decrease varicella outbreaks in schools in China, especially in provinces where VarV is not introduced into EPI.
入学疫苗接种记录检查策略（SECS）是一个为学生推荐疫苗的适当机会，以提高疫苗接种覆盖率（VC）。然而，它仅用于为在中国错过扩大免疫规划（EPI）疫苗的学生提供必要的补种。我们旨在解决这一差距，并量化 SECS 政策与水痘疫苗（VarV）覆盖率增加之间的关系。
我们采用了预测试和后测试准实验设计，以检验升级后的 SECS 政策对 2019-2020 年在六安新入学学生 VarV 覆盖率变化的影响。
800 名参与者被随机分为对照组（C 组，31.8%）、电话干预组（T 组，31.2%）和书面通知干预组（W 组，37.0%）。共有 84 名学生在研究期间接种了 VarV，VC 为 10.5%。T 组（RR=4.9，95%CI：2.2-10.9）和 W 组（RR=5.2，95%CI：2.4-11.5）的接种可能性明显高于 C 组（<.001）。
我们的研究表明，升级后的 SECS 对提高 VarV 的 VC 产生了积极影响。这种推动策略可能会减少中国学校的水痘暴发，特别是在 VarV 未被纳入 EPI 的省份。
