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高覆盖率与延迟接种剂量:北京市朝阳区4至12岁儿童家长对水痘疫苗的接受度和接种情况横断面研究。

High coverage with delayed doses: Cross-sectional study of parental acceptance and uptake of varicella vaccination in children aged 4-12 years in Chaoyang District, Beijing.

作者信息

Cao Yang, Li Xinyu, Zhao Ziwei, Li Zhen, Liu Fang, Liu Pu, Ma Jianxin, Shi Qian, Zhang Nan, Jia Bin

机构信息

Chaoyang District Center for Disease Control and Prevention, Beijing, China.

School of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.

出版信息

Hum Vaccin Immunother. 2025 Dec;21(1):2558271. doi: 10.1080/21645515.2025.2558271. Epub 2025 Sep 15.

Abstract

Regional disparities exist in China's varicella vaccination policies, with Beijing's voluntary two-dose program requiring self-payment having been implemented for more than a decade. In this study, we investigated parental acceptance and vaccination patterns among 2,189 children aged 4-12 years in Beijing's Chaoyang District, where policy integration is under consideration. The results revealed high baseline vaccination willingness (81.8%), potentially increasing to 86.3% with inclusion of an immunization program. Key determinants extended beyond demographic factors and disease knowledge to include parental satisfaction with immunization services and utilization of parenting apps. Current coverage rates were 74.5% for the first dose (VarV1) versus 53.2% for the second dose (VarV2), indicating significant second-dose attrition. Primary barriers to vaccination included limited awareness of the option to vaccinate, safety concerns, and perceptions that a single dose offers sufficient protection. Notably, 58.8% of children received VarV1 later than the recommended schedule, partly due to vaccination scheduling. School-based verification requirements emerged as a critical driver of compliance. Our study provides actionable insights for immunization policy optimization. We advocate targeted communication strategies via new media platforms, such as parenting apps, to address knowledge gaps, emphasize two-dose protocols, and boost vaccine confidence. This approach fosters a cycle of tool usage, knowledge acquisition, and timely vaccination, leveraging the demonstrated synergy between app usage and vaccine knowledge in enhancing adherence.

摘要

中国水痘疫苗接种政策存在地区差异,北京实施的自愿自费两剂次接种计划已推行了十多年。在本研究中,我们调查了北京市朝阳区2189名4至12岁儿童的家长接受度和接种模式,该地区正在考虑政策整合。结果显示,基线接种意愿较高(81.8%),若纳入免疫规划,这一比例可能升至86.3%。关键决定因素不仅包括人口统计学因素和疾病知识,还包括家长对免疫服务的满意度以及育儿应用程序的使用情况。目前,第一剂(VarV1)接种率为74.5%,而第二剂(VarV2)接种率为53.2%,表明第二剂接种率显著下降。接种的主要障碍包括对接种选择的认识有限、安全担忧以及认为单剂接种就足以提供保护。值得注意的是,58.8%的儿童接种VarV1的时间晚于推荐时间表,部分原因是接种安排。基于学校的核查要求成为提高依从性的关键驱动因素。我们的研究为优化免疫政策提供了可操作的见解。我们提倡通过新媒体平台(如育儿应用程序)采用有针对性的沟通策略,以解决知识差距、强调两剂接种方案并增强疫苗信心。这种方法利用应用程序使用与疫苗知识之间已证明的协同作用来提高依从性,从而促进工具使用、知识获取和及时接种的循环。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e22/12439547/3baa9082ca8a/KHVI_A_2558271_F0001_OC.jpg

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