Schrey M, Esser E
Dtsch Zahnarztl Z. 1978 Feb;33(2):143-5.
Vitamin A acid (VAS) has proved itself an effective local therapeutic agent for intra-oral leucoplakia. Clinical remission characterized by a decrease in horny lumps and the eosinophilic index and an increase in intermediary cells was achieved in 32 out of 50 cases. In the course of maintenance therapy development towards an exfoliocytologically healthy mucosa proceeds via increasing parakeratosis. VAS therapy is essentially thought of as symptomatic therapy.
维甲酸已证明是治疗口腔白斑的一种有效局部治疗剂。50例患者中有32例实现了临床缓解，表现为角质肿块和嗜酸性指数降低，中间细胞增加。在维持治疗过程中，通过增加不全角化，向脱落细胞学健康的黏膜发展。维甲酸治疗本质上被认为是对症治疗。
