Department of Otorhinolaryngology-Head and Neck Surgery, Korea University Medicine, Korea University Ansan Hospital, Ansan, South Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, Korea University Medicine, Korea University Anam Hospital, Seoul, South Korea.
Int J Pediatr Otorhinolaryngol. 2021 Jul;146:110775. doi: 10.1016/j.ijporl.2021.110775. Epub 2021 May 15.
The objective of the study was to analyze the auditory brainstem response (ABR) test results of adolescents with normal hearing threshold who have subjective tinnitus in an effort to determine the probable site of origin of tinnitus.
Among the patients who visited the outpatient clinic of the Department of Otolaryngology at our tertiary hospital from January 2016 to December 2019, adolescents aged 13-18 years with the chief complaint of unilateral subjective tinnitus and pure tone audiometry (PTA) within 25 dB HL were enrolled and retrospectively reviewed. The ABR test parameters (amplitudes and latencies of waves I, III, and V and interpeak latencies [IPLs] of waves I-III, III-V, and I-V) were analyzed and compared between tinnitus ears and contralateral ears without tinnitus. Study participants were divided into the chronic tinnitus (tinnitus duration ≥6 months) and non-chronic tinnitus (tinnitus duration <6 months) groups, and the difference between the two groups was analyzed.
Ten adolescents were included in the study, and their ABR test results were reviewed. IPL III-V was significantly prolonged in tinnitus ears compared to non-tinnitus ears (p = 0.035). Although other parameters were found to be statistically non-significant, there was preponderance in ABR wave I amplitude; it was smaller in tinnitus ears of chronic tinnitus adolescents than in those of non-chronic tinnitus adolescents (p = 0.114).
The probable site of origin of tinnitus in adolescents with normal hearing might be in the upper brainstem of the auditory pathway. Further analysis of ABR test results in adolescents with tinnitus and normal hearing can help clarify the pathophysiology of tinnitus in adolescents.
本研究旨在分析听力正常但有主观性耳鸣的青少年的听性脑干反应（ABR）测试结果，以确定耳鸣的可能起源部位。
在 2016 年 1 月至 2019 年 12 月期间，我们在耳鼻喉科门诊对主诉为单侧主观性耳鸣且纯音听阈（PTA）在 25dBHL 以内的 13-18 岁青少年进行回顾性分析。分析并比较耳鸣耳和无耳鸣对侧耳的 ABR 测试参数（波 I、III、V 的振幅和潜伏期以及波 I-III、III-V、I-V 的峰间潜伏期 [IPL]）。将研究参与者分为慢性耳鸣（耳鸣持续时间≥6 个月）和非慢性耳鸣（耳鸣持续时间<6 个月）组，并分析两组之间的差异。
研究纳入了 10 名青少年，对其 ABR 测试结果进行了回顾。与非耳鸣耳相比，耳鸣耳的 IPL III-V 明显延长（p=0.035）。虽然其他参数的统计学差异无显著性，但 ABR 波 I 振幅有倾向于变小的趋势，慢性耳鸣青少年的耳鸣耳的波 I 振幅小于非慢性耳鸣青少年（p=0.114）。
听力正常的青少年耳鸣的可能起源部位可能在上脑干听觉通路上。对有耳鸣和听力正常的青少年的 ABR 测试结果进行进一步分析，可以帮助阐明青少年耳鸣的病理生理学。
