Bak M, Asschenfeldt P
Institute of Pathology, Aalborg Hospital, Odense, Denmark.
Dis Colon Rectum. 1988 Aug;31(8):605-12. doi: 10.1007/BF02556796.
Adenocarcinoid of the appendix is a tumor that shares the histologic features of both carcinoids and adenocarcinomas. The metastatic ability of the tumor is uncertain. Twenty consecutive cases of adenocarcinoids were compared with 88 cases of conventional appendiceal carcinoids. Metastatic tumor spread was found in six of 20 cases of adenocarcinoids, but in none of the conventional carcinoids. Metastasizing tumors were characterized by a moderate to severe nuclear atypia and a high mitotic count. These features were present in only two of the nonmetastasizing tumors, one of which was treated by hemicolectomy. Adenocarcinoids showing moderate or severe nuclear atypia, a mitotic count of two or more mitoses/10 high power fields, or spread beyond the appendix should be treated by hemicolectomy. If these features are not present, simple appendectomy is adequate.
阑尾腺类癌是一种兼具类癌和腺癌组织学特征的肿瘤。该肿瘤的转移能力尚不确定。将连续20例阑尾腺类癌病例与88例传统阑尾类癌病例进行了比较。在20例阑尾腺类癌病例中有6例发现有转移瘤扩散，但在传统类癌病例中均未发现。发生转移的肿瘤具有中度至重度核异型性和高有丝分裂计数的特征。这些特征仅在两例未发生转移的肿瘤中出现，其中一例接受了半结肠切除术。表现出中度或重度核异型性、有丝分裂计数为两个或更多有丝分裂/10个高倍视野或扩散至阑尾以外的阑尾腺类癌应采用半结肠切除术治疗。如果不存在这些特征，单纯阑尾切除术就足够了。
