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[测定血浆3-甲氧基-4-羟基苯乙二醇的主要方法]

[Principle methods of determining plasma 3-methoxy-4-hydroxyphenyl glycol].

作者信息

Candito M, Chambon P

机构信息

Laboratoire de Biochimie, Hôpital Pasteur, CHR de Nice.

出版信息

Encephale. 1988 May-Jun;14(3):105-8.

PMID:3402378
Abstract

The dosage of plasma 3-methoxy-4-hydroxyphényl glycol (MHPG) presents a great interest, specially in psychiatry. Several methods are described: gas chromatography, with or without mass spectrometry, high performance liquid chromatography with some internal standard problems and with different modes of extractions and radioimmunoassay. Every method presents advantages but also inconveniences which are discussed.

摘要

血浆3-甲氧基-4-羟基苯乙二醇（MHPG）的剂量备受关注，尤其是在精神病学领域。文中描述了几种方法：气相色谱法（有无质谱联用）、存在一些内标问题且有不同提取模式的高效液相色谱法以及放射免疫分析法。每种方法都有其优点，但也存在一些有待讨论的不便之处。

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