Relationship Status Update on Astrocytic VEGFR-3 and mTOR Signaling: It's Complicated.
作者信息
Brewster Amy L
出版信息
Epilepsy Curr. 2021 Jan 28;21(2):117-119. doi: 10.1177/1535759720988541. eCollection 2021 Mar-Apr.
Abstract
摘要
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Relationship Status Update on Astrocytic VEGFR-3 and mTOR Signaling: It's Complicated.
Epilepsy Curr. 2021 Jan 28;21(2):117-119. doi: 10.1177/1535759720988541. eCollection 2021 Mar-Apr.
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Tuberous Sclerosis Complex as Disease Model for Investigating mTOR-Related Gliopathy During Epileptogenesis.结节性硬化症作为研究癫痫发生过程中mTOR相关神经胶质病变的疾病模型。
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Vascular endothelial growth factor receptor-3 regulates astroglial glutamate transporter-1 expression via mTOR activation in reactive astrocytes following pilocarpine-induced status epilepticus.血管内皮生长因子受体-3 通过雷帕霉素激活反应性星形胶质细胞中的 mTOR 调节癫痫持续状态后匹罗卡品诱导的星形胶质细胞谷氨酸转运体-1 的表达。
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Emerging Roles for Microglial Phagocytic Signaling in Epilepsy.小胶质细胞吞噬信号在癫痫中的新作用
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Post-translational Regulation of GLT-1 in Neurological Diseases and Its Potential as an Effective Therapeutic Target.神经疾病中GLT-1的翻译后调控及其作为有效治疗靶点的潜力
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Vascular endothelial growth factor (VEGF) and its role in the central nervous system: a new element in the neurotrophic hypothesis of antidepressant drug action.血管内皮生长因子（VEGF）及其在中枢神经系统中的作用：抗抑郁药作用的神经营养假说中的新元素。
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Vascular endothelial growth factor is up-regulated after status epilepticus and protects against seizure-induced neuronal loss in hippocampus.癫痫持续状态后血管内皮生长因子上调，并可防止海马体中癫痫发作诱导的神经元丢失。
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The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia.磷脂酰肌醇-3激酶/蛋白激酶B信号通路介导血管内皮生长因子的神经保护活性，并在局灶性脑缺血后诱导血脑屏障通透性增加。
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Vascular endothelial growth factor (VEGF) in seizures: a double-edged sword.癫痫中的血管内皮生长因子（VEGF）：一把双刃剑。
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