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输尿管肿瘤与肾盂肾盏肿瘤患者的生存差异：一项系统评价和荟萃分析。

Survival differences of patients with ureteral versus pelvicalyceal tumours: a systematic review and meta-analysis.

作者信息

Kaczmarek Krystian, Lemiński Artur, Gołąb Adam, Słojewski Marcin

机构信息

Department of Urology and Urological Oncology, Pomeranian Medical University, Szczecin, Poland.

出版信息

Arch Med Sci. 2019 Nov 21;17(3):603-612. doi: 10.5114/aoms.2019.89893. eCollection 2021.

DOI:10.5114/aoms.2019.89893
PMID:34025829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8130483/
Abstract

INTRODUCTION

Worse survival in upper tract urothelial carcinoma (UTUC) in the presence of a tumour in the ureter vs. pelvicalyceal tumours is reported in some studies; however, the definition of ureteral involvement (UI) varies across studies. We systematically evaluated evidence regarding the prognostic role of UI in overall and cancer-specific survival of patients with UTUC.

MATERIAL AND METHODS

A systematic search of PubMed, Scopus and Web of Knowledge was performed in March 2018.

RESULTS

The results were presented as a comparison between ureteral vs. pelvicalyceal tumours. A total of 14,895 patients were identified. Cumulative analyses indicated that UI worsens cancer-specific survival (CSS) and overall survival (OS), with a pooled HR of 1.52 ( < 0.001) and 1.39 ( = 0.004), respectively.

CONCLUSIONS

Our meta-analysis identified UI in UTUC as an adverse prognostic factor.

摘要

引言

一些研究报告称，输尿管存在肿瘤的上尿路尿路上皮癌（UTUC）患者的生存率低于肾盂肿瘤患者；然而，各研究中输尿管受累（UI）的定义有所不同。我们系统地评估了关于UI对UTUC患者总生存和癌症特异性生存的预后作用的证据。

材料与方法

2018年3月对PubMed、Scopus和Web of Knowledge进行了系统检索。

结果

结果以输尿管肿瘤与肾盂肿瘤的比较形式呈现。共识别出14895例患者。累积分析表明，UI会使癌症特异性生存（CSS）和总生存（OS）恶化，合并风险比分别为1.52（<0.001）和1.39（=0.004）。

结论

我们的荟萃分析确定UTUC中的UI是一个不良预后因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/564a/8130483/989723569f79/AMS-17-3-89895-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/564a/8130483/c82736011ed5/AMS-17-3-89895-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/564a/8130483/d3c19f7fc38f/AMS-17-3-89895-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/564a/8130483/2ae3bd2e55c3/AMS-17-3-89895-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/564a/8130483/4681884a82fd/AMS-17-3-89895-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/564a/8130483/989723569f79/AMS-17-3-89895-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/564a/8130483/c82736011ed5/AMS-17-3-89895-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/564a/8130483/d3c19f7fc38f/AMS-17-3-89895-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/564a/8130483/2ae3bd2e55c3/AMS-17-3-89895-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/564a/8130483/4681884a82fd/AMS-17-3-89895-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/564a/8130483/989723569f79/AMS-17-3-89895-g005.jpg

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本文引用的文献

1
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2017 Update.欧洲泌尿外科学会上尿路尿路上皮癌指南：2017 年更新版。
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2
Ureteral Involvement Is Associated with Poor Prognosis in Upper Urinary Tract Urothelial Carcinoma Patients Treated by Nephroureterectomy: A Multicenter Database Study.输尿管受累与接受肾输尿管切除术治疗的上尿路尿路上皮癌患者的不良预后相关：一项多中心数据库研究。
Eur Urol Focus. 2016 Aug;2(3):296-302. doi: 10.1016/j.euf.2015.10.008. Epub 2015 Nov 26.
3
Cancer Statistics, 2017.
肌肉浸润性上尿路尿路上皮癌的影像学预测指标：一项加拿大队列研究
Can Urol Assoc J. 2024 Dec;18(12):413-418. doi: 10.5489/cuaj.8817.
4
Adjuvant Chemotherapy in Patients with Locally Advanced Upper Tract Urothelial Carcinoma with or without Kidney Transplantation.局部晚期上尿路尿路上皮癌患者伴或不伴肾移植的辅助化疗
J Clin Med. 2024 Mar 22;13(7):1831. doi: 10.3390/jcm13071831.
5
Upper Tract Urothelial Carcinoma: A Narrative Review of Current Surveillance Strategies for Non-Metastatic Disease.上尿路尿路上皮癌：非转移性疾病当前监测策略的叙述性综述
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6
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7
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