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一名婴儿的多系统朗格汉斯细胞组织细胞增多症

Multisystem Langerhans Cell Histiocytosis in an infant.

作者信息

Ji William, Ladner Joshua, Rambie Aimee, Boyer Kathleen

机构信息

Department of Radiology, Madigan Army Medical Center, 9040A Jackson Ave, Joint Base Lewis-McChord, WA 98431, USA.

出版信息

Radiol Case Rep. 2021 May 6;16(7):1798-1805. doi: 10.1016/j.radcr.2021.04.028. eCollection 2021 Jul.

DOI:10.1016/j.radcr.2021.04.028
PMID:34025890
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8120863/
Abstract

Langerhans cell histiocytosis (LCH) is a rare enigmatic disease that pre-dominantly affects children under 5 years of age. We report an interesting case of a 5 month old female diagnosed with multisystem LCH. Her disease process included osseous, pulmonary, gastrointestinal, cutaneous, hematopoietic and neurologic involvement. This case highlights the varying clinical symptoms, risk factors, pathogenesis, and management of multisystem LCH. This case also emphasizes the role of diagnostic imaging in this multifaceted disease.

摘要

朗格汉斯细胞组织细胞增多症（LCH）是一种罕见的疑难病症，主要影响5岁以下儿童。我们报告了一例有趣的病例，一名5个月大的女性被诊断为多系统LCH。她的病程包括骨骼、肺部、胃肠道、皮肤、造血系统和神经系统受累。该病例突出了多系统LCH的不同临床症状、危险因素、发病机制及治疗。该病例还强调了诊断性影像学在这种多方面疾病中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/5ec071ca5e31/gr12.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/607e4952cbbb/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/5ec071ca5e31/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/813692113c98/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/177ba82937db/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/9fd5b2b625dc/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/cec1641db50c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/5cc09014957f/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/8cf65f8283b6/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/cf0e16c80cf2/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/f2698bebe87e/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/d1fe2df6b927/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/f535a9a51eb0/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/607e4952cbbb/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f2/8120863/5ec071ca5e31/gr12.jpg

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