Thang Nguyen Manh, Thien Dang Hong, Huyen Anh Nguyen Thi, Cuong Tran Danh
Department of Obstetrics and Gynecology, Hanoi Medical University, Hanoi, Viet Nam.
National Hospital of Obstetrics and Gynecology, Hanoi, Viet Nam.
Ann Med Surg (Lond). 2021 May 5;66:102377. doi: 10.1016/j.amsu.2021.102377. eCollection 2021 Jun.
Leiomyomatosis peritonealis disseminata (LPD) is a rare disease that can be challenging to diagnose. In this report, we present a case of LPD arising 5 years after laparoscopic uterine myomectomy using a power morcellator.
A 32-year-old woman was admitted to our hospital with complaints of vaginal bleeding and abdominal discomfort. Five years previously, she had undergone laparoscopic uterine myomectomy using a power morcellator. Pelvic ultrasonography and magnetic resonance imaging demonstrated multiple pelvic tumors closely attached to peritoneum with no indication of malignancy. An exploratory laparotomy revealed multiple sites of leiomyomatosis in the peritoneum, especially on the parietal peritoneum at the port site of the previous laparoscopic surgery. We surgically removed all visible tumors and performed a total hysterectomy. Histologic examination confirmed the diagnosis of LPD.
The use of a power morcellator without in-bag containment system might have played a role in the pathogenesis of LPD in our case. Ultrasonography, computed tomography, and MRI are among the most effective to distinguish between leiomyomas and other solid tumors in the pelvis, but they are not of great help in the differential diagnosis of malignancies.
The physicians need to combine medical history, clinical findings, imaging techniques and histopathological examination to establish a correct diagnosis of LPD. The application of containment bags in the setting of power morcellation should be considered to reduce the risk of developing LPD. The optimal intervention strategy should be chosen according to the particular features of each patient.
播散性腹膜平滑肌瘤病(LPD)是一种罕见疾病,诊断可能具有挑战性。在本报告中,我们介绍了一例在使用电动粉碎器进行腹腔镜子宫肌瘤切除术后5年发生的LPD病例。
一名32岁女性因阴道出血和腹部不适入院。5年前,她接受了使用电动粉碎器的腹腔镜子宫肌瘤切除术。盆腔超声和磁共振成像显示多个盆腔肿瘤紧密附着于腹膜,无恶性迹象。剖腹探查发现腹膜多处存在平滑肌瘤病,尤其是在前次腹腔镜手术切口部位的壁层腹膜。我们手术切除了所有可见肿瘤并进行了全子宫切除术。组织学检查确诊为LPD。
在我们的病例中,使用没有内置袋系统的电动粉碎器可能在LPD的发病机制中起了作用。超声、计算机断层扫描和磁共振成像在区分盆腔平滑肌瘤和其他实体肿瘤方面是最有效的方法之一,但在恶性肿瘤的鉴别诊断中帮助不大。
医生需要结合病史、临床表现、影像学技术和组织病理学检查来正确诊断LPD。应考虑在电动粉碎术时应用 containment bags 以降低发生LPD的风险。应根据每位患者的具体特征选择最佳干预策略。