Erwes Thomas, Abrantes-Figueiredo Jessica
Department of Medicine, UConn Health, Farmington, CT, 06030, United States.
Department of Medicine - Infectious Disease, Saint Francis Hospital and Medical Center, Hartford, CT, 06105, United States.
IDCases. 2021 May 7;24:e01150. doi: 10.1016/j.idcr.2021.e01150. eCollection 2021.
is an uncommon gram-negative bacterium that has rarely been identified as the causative organism in severe infections. Few cases have been described and have included patients with pneumonia, urinary tract infections or cholangitis. Only one case has reported to involve a liver abscess, thought to be from a primary urologic source. We describe the case of a 73-year-old man with recently diagnosed hepatocellular carcinoma who developed multiple pyogenic liver abscesses. The abscesses were thought to have developed in the setting of recent transarterial chemoembolization leading to bacteremia noted on admission. Treatment with ceftriaxone and metronidazole was initiated in addition to drainage of the abscesses, resulting in decreased size of liver collections and initial clinical improvement. remains a rare infectious organism in severe infections affecting both immunocompromised and immunocompetent individuals. Our patient's underlying malignancy and recent transarterial chemoembolization likely placed him at risk of liver abscess formation complicated by bacteremia and sepsis.
是一种罕见的革兰氏阴性菌,很少被确定为严重感染的病原体。已描述的病例很少,包括肺炎、尿路感染或胆管炎患者。仅有一例报告涉及肝脓肿,认为源于原发性泌尿系统感染。我们描述了一例73岁男性患者,近期诊断为肝细胞癌,并发多发性化脓性肝脓肿。这些脓肿被认为是在近期经动脉化疗栓塞后发生的,入院时发现有菌血症。除了脓肿引流外,还开始使用头孢曲松和甲硝唑治疗,肝内积液体积减小,临床症状初步改善。在影响免疫功能低下和免疫功能正常个体的严重感染中,仍然是一种罕见的感染病原体。我们患者的潜在恶性肿瘤和近期的经动脉化疗栓塞可能使他有发生肝脓肿形成并伴有菌血症和败血症的风险。