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一名免疫功能正常的患者患隐球菌性脑膜炎,并伴有多发性脑梗死。

Cryptococcus meningitis presented with multiple cerebral infarcts in an immunocompetent patient.

作者信息

Erturk Sengel Buket, Tukenmez Tigen Elif, Can Sarinoglu Rabia, Midi Ipek, Cerikcioglu Nilgun, Odabasi Zekaver

机构信息

Marmara University, Faculty of Medicine, Infectious Disease and Clinical Microbiology, Istanbul, Turkey.

Marmara University, Faculty of Medicine, Medical Microbiology, Istanbul, Turkey.

出版信息

IDCases. 2021 May 7;24:e01154. doi: 10.1016/j.idcr.2021.e01154. eCollection 2021.

Abstract

is generally observed with immunosuppressive conditions. Rarely, it may be seen in immunocompetent individuals and presented with non-specific conditions. We described an immunocompetent case of cryptococcal meningitis presented with multiple cerebral infarcts. Despite the late diagnosis and emergence of hydrocephalus during treatment, the patient was recovered without any sequelae. In immunocompetent patients, the conventional diagnostics tests may be negative because of the low fungal load. If it is available, the Biofire FilmArray meningitis panel has high sensitivity and specificity for diagnosis.

摘要

通常在免疫抑制情况下观察到。很少见的是,它可能在免疫功能正常的个体中出现,并伴有非特异性病症。我们描述了一例免疫功能正常的隐球菌性脑膜炎病例,该病例伴有多发性脑梗死。尽管诊断较晚且治疗期间出现了脑积水,但患者康复后没有任何后遗症。在免疫功能正常的患者中,由于真菌载量低,传统诊断测试可能为阴性。如果有条件,Biofire FilmArray脑膜炎检测板对诊断具有高灵敏度和特异性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23ca/8131984/668133269978/gr1.jpg

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