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在已消除麻疹的国家出现麻疹:日本一名感染麻疹的产后母亲及婴儿的病例报告。

Measles in a measles-eliminated country: A case report of a measles-infected postpartum mother and infant in Japan.

作者信息

Mito Haruki, Hase Ryota, Oshima Nozomu, Ikeda Hiroyuki

机构信息

Department of Infectious Diseases, Japanese Red Cross Narita Hospital, 90-1 Iida-cho, Narita, Chiba, 286-8523, Japan.

Department of Infectious Diseases, Kameda Medical Center, 929 Higashi-cho, Kamogawa, Chiba, 296-8602, Japan.

出版信息

IDCases. 2021 May 9;24:e01157. doi: 10.1016/j.idcr.2021.e01157. eCollection 2021.

DOI:10.1016/j.idcr.2021.e01157
PMID:34026544
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8131988/
Abstract

Japan has maintained measles elimination status since 2015. However, sporadic outbreaks of measles have been continuously reported. Here, we report a case of a measles-infected postpartum mother and infant in Japan. A 28-year-old Japanese woman, who had previously received a dose of the measles vaccination, experienced fever 5 days postpartum. Subsequently, a maculopapular rash appeared, and she was diagnosed with measles. Moreover, her baby developed a fever and maculopapular rash on the 13th day of life, 2 days after postexposure prophylaxis with intravenous immunoglobulin, and was also diagnosed with measles. Both showed full recovery. This case suggests that measles can still be a threat in a measles-eliminated country, and the administration of two doses of measles vaccination to women prior to childbearing age is crucial to protect newborns from measles.

摘要

自2015年以来,日本一直保持麻疹消除状态。然而,仍不断有麻疹散发病例的报告。在此,我们报告一例日本麻疹感染的产后母婴病例。一名28岁的日本女性,此前曾接种过一剂麻疹疫苗,产后5天出现发热。随后出现斑丘疹,被诊断为麻疹。此外,她的婴儿在出生后第13天,即在接受静脉注射免疫球蛋白进行暴露后预防2天后,出现发热和斑丘疹,也被诊断为麻疹。两人均完全康复。该病例表明,在已消除麻疹的国家,麻疹仍然可能构成威胁,育龄妇女接种两剂麻疹疫苗对于保护新生儿免受麻疹感染至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ce/8131988/5ed03f11b43a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ce/8131988/7c658148e5b5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ce/8131988/5ed03f11b43a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ce/8131988/7c658148e5b5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ce/8131988/5ed03f11b43a/gr2.jpg

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本文引用的文献

1
Factors Associated With Measles Transmission in the United States During the Postelimination Era.美国消除麻疹后时代与麻疹传播相关的因素
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Measles elimination and immunisation: national surveillance trends in Japan, 2008-2015.麻疹消除与免疫:2008 - 2015年日本国家监测趋势
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Field effectiveness of live attenuated measles-containing vaccines: a review of published literature.含麻疹成分减毒活疫苗的现场效力:已发表文献综述。
J Infect Dis. 2011 Jul;204 Suppl 1:S133-48. doi: 10.1093/infdis/jir102.
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