Enes Silva João, Pinelas Sofia, Pacheco Mariana, Patacho Marta, Almeida Jorge
Centro Hospitalar Universitário do Porto EPE, Internal Medicine Department, Alameda Prof. Hernâni Monteiro, Porto, PT 4200-319, Portugal.
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Medical Oncology Department, Rua Dr. António Bernardino de Almeida, Porto, PT 4200-072, Portugal.
IDCases. 2021 May 12;24:e01159. doi: 10.1016/j.idcr.2021.e01159. eCollection 2021.
A 70-year-old woman presented to the emergency department with a 3-week history of prolonged fever, asthenia and anorexia, denying other symptoms. Physical examination was unremarkable and the patient admitted for further investigation. Initial laboratory testing showed leucocytosis, elevated C-reactive protein and cholestasis, without hyperbilirubinemia or cytolysis. Abdominal ultrasonography found no abnormalities. Viral serologies, autoimmune tests and blood cultures were collected for further investigation of causes of prolonged fever with hepatic involvement. After two days, C was isolated in blood cultures and intravenous (IV) piperacillin-tazobactam initiated. Computed tomography (CT) scan of the abdomen showed a left lobe hepatic abscess with gas and a linear hyperdense image, possibly a foreign body, piercing through the gastric antrum into the abscess. Surgical exploration was done for source control. The abscess was drained and the foreign body, a 3.5 cm long fishbone, was removed. The patient's condition rapidly improved. Gastrointestinal perforation due to the ingestion of sharp and elongated foreign bodies usually occur in ileal loops, where the intestinal wall is thinner, causing extravasation of fluids and air into the peritoneum and typically presents with an acute abdomen. The uncommon location of perforation masked these symptoms leading to the unusual presentation with prolonged fever.
一名70岁女性因持续发热、乏力和厌食3周就诊于急诊科,否认有其他症状。体格检查无异常,该患者入院作进一步检查。初始实验室检查显示白细胞增多、C反应蛋白升高及胆汁淤积,但无高胆红素血症或细胞溶解。腹部超声检查未发现异常。采集病毒血清学、自身免疫检查及血培养样本,以进一步调查伴有肝脏受累的长期发热病因。两天后,血培养分离出C菌,开始静脉注射哌拉西林-他唑巴坦。腹部计算机断层扫描(CT)显示肝左叶脓肿伴气体形成以及一个线性高密度影像,可能是一个异物,经胃窦穿入脓肿。为控制感染源进行了手术探查。脓肿得以引流,取出了异物,一根3.5厘米长的鱼骨。患者病情迅速好转。因吞食尖锐细长异物导致的胃肠道穿孔通常发生在肠壁较薄的回肠袢,会引起液体和空气渗入腹膜,典型表现为急腹症。穿孔的罕见位置掩盖了这些症状,导致出现以长期发热为特征的不寻常表现。