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使用网状脱细胞真皮基质进行胸大肌前乳房植入重建术

Prepectoral Implant-Based Breast Reconstruction Using Meshed ADM.

作者信息

Fin Alessandra, De Biasio Fabrizio, Mura Sebastiano, Massarut Samuele, Zaccaria Giovanna, Parodi Pier Camillo

机构信息

Clinic of Plastic and Reconstructive Surgery, Academic Hospital of Udine, Department of Medical Area, University of Udine, Italy.

Department of Breast Surgery, Centro di Riferimento Oncologico (CRO), Aviano, Pordenone.

出版信息

Plast Surg (Oakv). 2021 May;29(2):81-87. doi: 10.1177/2292550320933687. Epub 2020 Jun 19.

Abstract

Prepectoral prosthetic breast reconstruction has been widely reassessed in recent years and is taking on an increasingly important role in the field of immediate breast reconstruction. We report here a case series of 32 patients who underwent nipple-sparing mastectomy for breast carcinoma and prepectoral breast reconstruction involving an acellular dermal matrix (ADM) treated by means of a skin-graft mesher in our hospital from January 2015 to March 2016. The indications for this type of reconstruction were body mass index (BMI) less than 30 kg/m; no history of radiotherapy; no active smokers; moderate grade breast; and good viability of mastectomy flap: normal skin colour, active bleeding at the fresh cut edges, and thicker than 1 cm mastectomy flaps; the viability of lower thicknesses was ascertained by the fluorescent dye indocyanine green xenon-based imaging technology (4 patients). The mean age of the patients was 56.4 years (range: 39-77 years). Their mean BMI was 27.4 kg/m. Until the end of follow-up (mean: 17 months), major complications requiring reoperation occurred in 9% of patients and minor complications in 22% of patients. The mean of the 3 pain visual analogue scale scores taken in the first 24 hours after surgery was 1.8. Mean duration of hospital stay has been 2.2 days. Our complication rate was similar to those reported in other studies on prepectoral breast reconstruction featuring total ADM coverage of the implant.

摘要

近年来,胸前区假体乳房重建术得到了广泛的重新评估,并且在即刻乳房重建领域正发挥着越来越重要的作用。在此,我们报告一组32例患者的病例系列,这些患者于2015年1月至2016年3月在我院接受了保留乳头的乳腺癌乳房切除术及采用皮肤移植网片处理的脱细胞真皮基质(ADM)进行的胸前区乳房重建术。这类重建术的适应证为:体重指数(BMI)小于30kg/m²;无放疗史;无现吸烟者;乳腺为中度分级;乳房切除皮瓣活力良好:皮肤颜色正常、新鲜切口边缘有活跃出血且乳房切除皮瓣厚度大于1cm;厚度较薄者的活力通过基于荧光染料吲哚菁绿氙的成像技术确定(4例患者)。患者的平均年龄为56.4岁(范围:39 - 77岁)。他们的平均BMI为27.4kg/m²。直到随访结束(平均:17个月),9%的患者发生了需要再次手术的主要并发症,22%的患者发生了 minor 并发症。术后头24小时内采用的3次疼痛视觉模拟量表评分的平均值为1.8。平均住院时间为2.2天。我们的并发症发生率与其他关于胸前区乳房重建术(其特点为植入物完全由ADM覆盖)的研究报告的发生率相似。

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