Department of Paediatrics, Mardan Medical Complex, Mardan, Pakistan.
J Coll Physicians Surg Pak. 2021 May;31(5):576-581. doi: 10.29271/jcpsp.2021.05.576.
To study the clinical and laboratory profile in infants and children presented in the tertiary care hospital with poppy intake and to compare the profile between those who survived with those who died.
Observational study. Study Place and Duration: Department Of Paediatrics, Mardan Medical Complex, Mardan, KPK, Pakistan from January 2019 to January 2020.
All the infants and children who reported during research period with signs and symptoms (one or more) of opium poppy intoxication, i.e. meiosis, respiratory depression and decreased consciousness level along with confirmed history of giving poppy at home.
A total of 32 cases of opium poppy intoxication were admitted. Their age ranged from one month to 23 months, mean age was 7.22 + 5.43 months. Out of them, 15 (46.87%) infants and children survived, and 17 (53.13%) died, (p<0.001). The children who survived had significantly shorter period of time between poppy over-dose and admission in hospital as compared to those who had died (6.0 + 2.56 hours versus 12.47 + 4.14 hours, p<0.001). There was significantly high mortality in children who were given poppy powder mixed in water, out of 17 cases 13 died and 4 survived. Low respiratory rate, decreased oxygen saturation, aspiration pneumonia, apneic spells, cyanosis and leukocytosis >15000cc had significant effect on mortality.
Poppy opium is very dangerous and hazardous for infants as it depresses respiration, causes coma; and can be fatal. People need to be educated to curb this harmful practice and authorities need to take necessary actions to stop the sale of poppy at shops and stores. Key Words: Poppy, poisoning/Intoxication, Infants, Meiosis, Apneic spell.
研究在三级保健医院就诊的摄入罂粟的婴儿和儿童的临床和实验室特征，并比较存活者和死亡者的特征。
观察性研究。研究地点和时间：巴基斯坦开伯尔-普赫图赫瓦省马尔丹医疗综合体儿科，2019 年 1 月至 2020 年 1 月。
所有报告有罂粟中毒迹象和症状（一个或多个）的婴儿和儿童，即减数分裂、呼吸抑制和意识水平降低，以及在家中给予罂粟的确认病史。
共收治 32 例罂粟中毒病例。他们的年龄从一个月到 23 个月不等，平均年龄为 7.22 + 5.43 个月。其中 15 例（46.87%）婴儿和儿童存活，17 例（53.13%）死亡（p<0.001）。与死亡组相比，存活组在罂粟过量摄入和入院之间的时间明显较短（6.0 + 2.56 小时对 12.47 + 4.14 小时，p<0.001）。在给予混合在水中的罂粟粉的儿童中，死亡率明显较高，17 例中有 13 例死亡，4 例存活。低呼吸频率、低氧饱和度、吸入性肺炎、呼吸暂停发作、发绀和白细胞计数>15000cc 对死亡率有显著影响。
罂粟鸦片对婴儿非常危险和有害，因为它会抑制呼吸，导致昏迷，甚至致命。需要对人们进行教育以遏制这种有害行为，当局需要采取必要措施阻止商店和商店销售罂粟。关键词：罂粟，中毒/中毒，婴儿，减数分裂，呼吸暂停发作。
