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利用全基因组关联研究鉴定 F2 鸡群体中与屠宰性状相关的候选基因。

Identification of candidate genes associated with slaughter traits in F2 chicken population using genome-wide association study.

机构信息

National Engineering Laboratory for Animal Breeding, Beijing Key Laboratory of Animal Genetic Improvement, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.

出版信息

Anim Genet. 2021 Aug;52(4):532-535. doi: 10.1111/age.13079. Epub 2021 May 24.

DOI:10.1111/age.13079
PMID:34028062
Abstract

Slaughter traits are crucial economic traits of chickens. We performed a GWAS to discover critical loci and candidate genes for 21 slaughter traits in an F2 chicken population resulting from crossing Luxi gamecocks and recessive white feather broilers. We found some SNPs and genes which were significantly associated with keel length, head length, body slope length, bilateral leg weight without shin, bilateral foot weight, subcutaneous fat thickness, heart weight, muscular stomach weight and glandular stomach weight. This study provides references for further investigation of slaughter traits and molecular breeding in chicken.

摘要

屠宰性状是鸡的重要经济性状。本研究利用鲁西斗鸡和隐性白羽肉鸡杂交构建的 F2 鸡群体,开展了 21 个屠宰性状的全基因组关联分析,鉴定到了一些与龙骨长度、头长、体斜长、无胫鸡腿重、双脚重、皮下脂肪厚度、心脏重、肌胃重和腺胃重等性状显著关联的 SNP 和候选基因,为鸡屠宰性状的深入研究和分子育种提供了参考。

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