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COVID-19 大流行期间的角膜移植:意大利眼库国家报告。

Corneal transplant during COVID-19 pandemic: the Italian Eye Bank national report.

机构信息

Ophthalmology Unit. Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

Eye Bank of Piedmont, SSD Tissue Banks and Biorepository, Città della Salute e della Scienza, Torino, Italy.

出版信息

Cell Tissue Bank. 2021 Dec;22(4):697-702. doi: 10.1007/s10561-021-09934-8. Epub 2021 May 24.

Abstract

To investigate the impact of Coronavirus Disease-2019 lockdown on the Italian Eye Bank organization. In this national retrospective, multicentric, cohort study, data from the Italian Eye Bank during both the lockdown and the first month after the lockdown period were retrieved. We compared the Italian Eye Bank metrics with the same timeframe of 2019 and 2018. Data from 13 out of 13 (100%) Italian Eye Banks were included in the analysis. A statistically significant reduction in the number of donor corneas retrieved in 2020 was found as compared to the same period in 2019 and in 2018, respectively (2020 = 1284; 2019 = 3088; 2018 = 3221; ANOVA: p < 0.0001). Only 534 corneas have been distributed by Eye Banks during the COVID-19-lockdown period (2020 = 534; 2019 = 1220; 2018 = 1237. ANOVA: p < 0.0001). Similarly, the number of wasted corneas due to postponed or cancelled surgeries was 421, resulting in a considerable increase as compared to the previous 2 years (2020 = 421; 2019 = 67; 2018 = 84; ANOVA: p = 0.0035). Overall, 45 donor corneas were rejected in accordance with the guidance of the Italian National Health Institute Italian National Transplant Centre (CNT). SARS-CoV-2 pandemic has profoundly affected every social and medical field, including the Eye Bank procurement and distribution programs. The current data collected from all the Italian Eye Banks highlights the present and the forthcoming difficulties that the Eye Bank community is going to experience, as for the ongoing pandemic.

摘要

为了调查 2019 年冠状病毒病封锁对意大利眼库组织的影响。在这项全国性回顾性、多中心队列研究中,检索了意大利眼库在封锁期间和封锁后第一个月的数据。我们将意大利眼库的数据与 2019 年和 2018 年同期的数据进行了比较。来自 13 个意大利眼库中的 13 个(100%)的数据被纳入分析。与 2019 年和 2018 年同期相比,2020 年可获取的供体角膜数量明显减少(2020 年=1284;2019 年=3088;2018 年=3221;方差分析:p<0.0001)。在 COVID-19 封锁期间,只有 534 个角膜由眼库分配(2020 年=534;2019 年=1220;2018 年=1237.方差分析:p<0.0001)。同样,由于手术推迟或取消而浪费的角膜数量为 421 个,与前两年相比显著增加(2020 年=421;2019 年=67;2018 年=84;方差分析:p=0.0035)。总体而言,根据意大利国家卫生研究所意大利国家移植中心(CNT)的指导意见,有 45 个供体角膜被拒绝。SARS-CoV-2 大流行深刻影响了包括眼库采购和配送计划在内的每一个社会和医疗领域。目前从所有意大利眼库收集的数据突出了眼库界目前和即将面临的困难,因为目前正在经历大流行。

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