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过去十年角膜移植概述

An Overview of Corneal Transplantation in the Past Decade.

作者信息

Musa Mutali, Zeppieri Marco, Enaholo Ehimare S, Chukwuyem Ekele, Salati Carlo

机构信息

Department of Optometry, University of Benin, Benin City 300238, Nigeria.

Department of Ophthalmology, University Hospital of Udine, 33100 Udine, Italy.

出版信息

Clin Pract. 2023 Feb 14;13(1):264-279. doi: 10.3390/clinpract13010024.

Abstract

The cornea is a transparent avascular structure located in the front of the eye that refracts light entering the eyes and also serves as a barrier between the outside world and the internal contents of the eye. Like every other body part, the cornea may suffer insult from trauma, infection, and inflammation. In the case of trauma, a prior infection that left a scar, or conditions such as keratoconus that warrant the removal of all or part of the cornea (keratoplasty), it is important to use healthy donor corneal tissues and cells that can replace the damaged cornea. The types of cornea transplant techniques employed currently include: penetrating keratoplasty, endothelial keratoplasty (EK), and artificial cornea transplant. Postoperative failure acutely or after years can result after a cornea transplant and may require a repeat transplant. This minireview briefly examines the various types of corneal transplant methodologies, indications, contraindications, presurgical protocols, sources of cornea transplant material, wound healing after surgery complications, co-morbidities, and the effect of COVID-19 in corneal transplant surgery.

摘要

角膜是位于眼球前部的透明无血管结构,它能折射进入眼睛的光线,并且作为外界与眼内组织之间的屏障。和身体的其他部位一样,角膜可能会受到外伤、感染和炎症的损害。在外伤、先前感染留下疤痕的情况下,或者诸如圆锥角膜等需要切除全部或部分角膜(角膜移植术)的病症中,使用健康的供体角膜组织和细胞来替代受损角膜非常重要。目前采用的角膜移植技术类型包括:穿透性角膜移植术、内皮角膜移植术(EK)和人工角膜移植。角膜移植术后可能会在急性情况下或数年后出现失败,可能需要再次移植。本综述简要探讨了各种类型的角膜移植方法、适应证、禁忌证、术前方案、角膜移植材料来源、术后伤口愈合、并发症、合并症以及新冠病毒肺炎对角膜移植手术的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fffc/9955122/5fbbf2969612/clinpract-13-00024-g001.jpg

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