School of Medicine, University of Western Australia, Nedlands, Western Australia, Australia.
Department of Haematology, Royal Perth Hospital, Perth, Western Australia, Australia.
Australas J Dermatol. 2021 Aug;62(3):e400-e403. doi: 10.1111/ajd.13606. Epub 2021 May 24.
We report the case of a 59-year-old woman with stage IV erythrodermic mycosis fungoides (MF) and large cell transformation who, despite failing multiple previous treatments, achieved complete remission through a combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation (alloSCT). Further studies are needed in focussing on this combined regimen in treating cutaneous T-cell lymphoma (CTCL) and its efficacy as a bridging regimen in facilitating successful alloSCT.
我们报告了一例 59 岁女性患者，患有 IV 期红皮病蕈样真菌病（MF）和大细胞转化，尽管之前的多种治疗均失败，但通过联合普拉曲沙和罗米地辛治疗后，再进行异基因造血干细胞移植（alloSCT），达到完全缓解。需要进一步研究这种联合方案治疗皮肤 T 细胞淋巴瘤（CTCL）及其作为桥接方案促进成功 alloSCT 的疗效。
