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无创伤性修复治疗管理幼儿龋病的成本效果分析:微观模拟模型。

Cost-effectiveness analysis of atraumatic restorative treatment to manage early childhood caries: microsimulation modelling.

机构信息

Deakin Health Economics, Institute for Health Transformation, Deakin University, Geelong, Victoria, Australia.

Dental Health Services, Bentley Delivery Centre, Perth, Western Australia, Australia.

出版信息

Aust Dent J. 2021 Mar;66 Suppl 1:S63-S70. doi: 10.1111/adj.12857. Epub 2021 Jun 22.

Abstract

BACKGROUND

This study assessed the cost-effectiveness of atraumatic restorative treatment and the Hall Technique approach (ART/HT) in managing dental caries in young children under the health provider perspective in order to explore a best-buy alternative to dental general anaesthesia (DGA).

METHODS

Sixty-five observations from a randomized controlled trial were used to construct 20 000 microsimulations representing individual-level clinical outcome and costs of the DGA and ART/HT. Outcome was percentage of successfully managed cases. Costs were reported in 2020 price. Three different scenarios with different assumptions of clinical success of the DGA and the ART/HT were analysed. Probabilistic sensitivity analysis was carried out.

RESULTS

The ART/HT successfully managed more cases at lower cost ($557) than the DGA when the system failure of the DGA was considered. Under per protocol analysis, participants in both arms were successfully managed, but the ART/HT costed $580 less than the DGA. Probabilistic sensitivity analysis confirmed the ART/HT was a dominant intervention.

CONCLUSIONS

The ART/HT approach was non-inferior in managing dental caries in young children but at lower costs than the DGA. The ART/HT could be a viable option in the provision of comprehensive dental care in locations with limited access to DGA and reduce hospital admission.

摘要

背景

本研究从医疗服务提供者的角度评估了非创伤性修复治疗和 Hall 技术(ART/HT)在治疗儿童龋齿方面的成本效益,以探索一种替代牙科全身麻醉(DGA)的最佳选择。

方法

使用来自一项随机对照试验的 65 个观察值,构建了 20000 个微观模拟,代表了 DGA 和 ART/HT 的个体临床结果和成本。结果为成功治疗病例的百分比。成本以 2020 年的价格报告。分析了三种不同的方案,这些方案对 DGA 和 ART/HT 的临床成功率有不同的假设。进行了概率敏感性分析。

结果

当考虑 DGA 系统故障时,ART/HT 以较低的成本($557)成功管理了更多的病例。在符合方案分析中,两个治疗组的参与者都成功地得到了治疗,但 ART/HT 的成本比 DGA 低$580。概率敏感性分析证实了 ART/HT 是一种占主导地位的干预措施。

结论

ART/HT 方法在治疗儿童龋齿方面不劣于 DGA,但成本更低。在 DGA 可及性有限的地方,ART/HT 可以作为提供全面牙科护理的一种可行选择,并减少住院治疗。

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