Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Basic Sciences in Infectious Diseases Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
J Clin Lab Anal. 2021 Jul;35(7):e23850. doi: 10.1002/jcla.23850. Epub 2021 May 24.
Superficial and cutaneous fungal infections are common in tropical areas. The aim of this study was to provide a basic database of superficial and cutaneous mycoses and the most common etiological agents among patients.
Between 2015 and 2019, a total of 1807 patients suspected of superficial and cutaneous mycosis referring to the mycology laboratory of Shiraz medical school, Fars, Iran were evaluated. Specimens were taken from the patients' affected area, and clinical samples were examined by direct microscopy and culture. The epidemiological profile of the patients was collected.
A total of 750 patients were confirmed with mycoses. Positive samples totaled 750 cases consisting of the nail (373/49.7%), skin (323/43%), head (47/6.26%), and mucosal membrane (4/0.5%). The yeasts group included 304 Candida spp. (70.3%), 123 Malassezia spp. (28.47%), and 5 Rhodotorula spp. (1.1%). The filamentous fungi were distributed as 34.8% dermatophytes and 7.5% non-dermatophyte. The clinical types of dermatophytosis were tinea unguium (110/261), tinea capitis (50/261), tinea pedis (48/261), tinea corporis (37/261), and tinea cruris (16/261). Non-dermatophyte molds included A. flavus 17, A. niger 4, Aspergillus spp. 15, Penicillium. 10, Fusarium 6, Mucor 2, Stemphylium 1, and Alternaria 1.
This study provides useful data for the study trends of superficial and cutaneous fungal infections in a specific area. The mycological data confirmed higher incidence of candidiasis (mainly onychomycosis) and dermatophytosis in patients affected by fungal pathogens, which helped to better understand the epidemiological aspects of these mycoses.
在热带地区，浅部和皮肤真菌感染很常见。本研究旨在为浅部和皮肤真菌病以及患者中最常见的病原微生物提供一个基本数据库。
2015 年至 2019 年期间，对来自伊朗法尔斯省设拉子医学院真菌学实验室的 1807 例疑似浅部和皮肤真菌感染的患者进行了评估。从患者的受影响区域采集标本，并通过直接显微镜检查和培养对临床标本进行检查。收集了患者的流行病学资料。
共有 750 例患者被确诊患有真菌病。阳性样本共计 750 例，包括指甲（373/49.7%）、皮肤（323/43%）、头部（47/6.26%）和黏膜（4/0.5%）。酵母组包括 304 株念珠菌属（70.3%）、123 株马拉色菌属（28.47%）和 5 株红酵母属（1.1%）。丝状真菌分布为 34.8%的皮肤癣菌和 7.5%的非皮肤癣菌。皮肤癣菌病的临床类型为甲真菌病（110/261）、头癣（50/261）、足癣（48/261）、体癣（37/261）和股癣（16/261）。非皮肤癣菌性霉菌包括黄曲霉 17 株、黑曲霉 4 株、曲霉属 15 株、青霉属 10 株、镰刀菌属 6 株、毛霉属 2 株、茎点霉属 1 株和链格孢属 1 株。
本研究为特定地区浅部和皮肤真菌感染研究趋势提供了有用的数据。真菌学数据证实，在受真菌病原体影响的患者中，念珠菌病（主要是甲真菌病）和皮肤癣菌病的发病率较高，这有助于更好地了解这些真菌感染的流行病学方面。
