From the Tulane University School of Medicine.
CrescentCare clinic, New Orleans, LA.
Sex Transm Dis. 2021 Aug 1;48(8):595-600. doi: 10.1097/OLQ.0000000000001484.
People experiencing homelessness are disproportionately infected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV). In response to COVID-19, cities nationwide temporarily housed people experiencing homelessness in unused hotels. One such initiative in New Orleans also enacted a screening, counseling, and linkage-to-care model for HIV and HCV treatment for this temporarily housed population between May and July 2020.
A nonconcurrent cohort study was performed assessing follow up in the treatment of HIV and HCV for this population. Outcome data were collected on seropositive patients' electronic medical record to assess patient progression through the treatment cascade.
Of 102 unhoused residents, 25 (24.5%) tested HCV seropositive. Of the HCV positive 21/25 (84%) were connected to the associated clinic for follow up care and 10 (40%) obtained HCV treatment medication. Furthermore, all 3 patients who tested seropositive for HIV either started or re-initiated antiviral treatment. The greatest barrier to providing medication for the HCV seropositive patients, once care was initiated, was loss-to-follow-up.
Targeting homeless persons living in temporary residences for HCV and HIV screening can be effective at promoting access to care for those infected due to this population's high HCV seropositivity especially significant if the patient has a history of intravenous drug use or is older than 40 years. However, continued outreach strategies are needed to assist patients in retention of care.
无家可归者感染人类免疫缺陷病毒(HIV)和丙型肝炎病毒(HCV)的比例不成比例。为应对 COVID-19,全美各地的城市将无家可归者临时安置在未使用的酒店中。新奥尔良的一项此类举措还在 2020 年 5 月至 7 月期间为这一临时收容人群实施了 HIV 和 HCV 治疗的筛查、咨询和转介服务模式。
本研究进行了一项非同期队列研究,以评估该人群中 HIV 和 HCV 治疗的随访情况。从电子病历中收集了血清阳性患者的结局数据,以评估患者在治疗阶梯中的进展情况。
在 102 名无家可归的居民中,25 人(24.5%) HCV 血清呈阳性。在 HCV 阳性的 25 人中,有 21 人(84%)与相关诊所建立了联系,接受后续护理,其中 10 人(40%)获得了 HCV 治疗药物。此外,所有 3 名 HIV 血清呈阳性的患者都开始或重新开始接受抗病毒治疗。为 HCV 血清阳性患者提供药物治疗的最大障碍是一旦开始治疗,患者就会失访。
针对居住在临时住所中的无家可归者进行 HCV 和 HIV 筛查,可以有效地促进对该人群中因 HCV 血清阳性率高而感染的人的治疗。如果患者有静脉吸毒史或年龄大于 40 岁,则这种筛查策略尤其重要。然而,仍需要继续开展外展策略,以帮助患者保持治疗。