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黄斑下视网膜色素上皮炎性病变表现为结核性多灶性脉络膜炎复发的体征。

Subfoveal retinal pigment epithelium inflammatory lesion presenting as a sign of reactivation of tubercular multifocal choroiditis.

作者信息

Kaza Hrishikesh, Gala Jignesh Manshibhai, Rani Padmaja Kumari

机构信息

Uveitis Service, L V Prasad Eye Institute, KAR Campus, Hyderabad, Telangana, India.

Smt Kannuri Santhamma Centre for Vitreoretinal Diseases, LV Prasad Eye Institute, KAR Campus, Hyderabad, Telangana, India.

出版信息

BMJ Case Rep. 2021 May 24;14(5):e240280. doi: 10.1136/bcr-2020-240280.

DOI:10.1136/bcr-2020-240280
PMID:34031072
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8149327/
Abstract

Multifocal choroiditis (MFC) can be associated with ocular tuberculosis (TB). Inflammatory peripapillary choroidal neovascular membrane (PPCNVM) is uncommon in TB MFC. Subretinal pigment epithelial inflammatory lesions are suggestive of acute inflammation or reactivation of inflammation in the setting of MFC. We present a case of MFC, of tubercular aetiology, during course of treatment of PPCNVM developed a subfoveal retinal pigment epithelial lesion. Clinical examination suggested a recurrence of PPCNVM, with the new macular lesions posing a dilemma of new onset inflammatory choroidal neovascular membrane (CNVM) at the macula versus reactivation of choroiditis at the posterior pole. Multimodal imaging helped differentiate the lesion from CNVM and give the appropriate antitubercular treatment to prevent future recurrences.

摘要

多灶性脉络膜炎(MFC)可与眼结核(TB)相关。炎性视乳头周围脉络膜新生血管膜(PPCNVM)在结核性MFC中并不常见。视网膜色素上皮下炎性病变提示MFC情况下的急性炎症或炎症再激活。我们报告一例病因结核的MFC病例,在PPCNVM治疗过程中出现了黄斑下视网膜色素上皮病变。临床检查提示PPCNVM复发,新的黄斑病变带来了黄斑区新发炎性脉络膜新生血管膜(CNVM)与后极部脉络膜炎再激活的两难局面。多模态成像有助于将该病变与CNVM区分开来,并给予适当的抗结核治疗以预防未来复发。

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Subfoveal retinal pigment epithelium inflammatory lesion presenting as a sign of reactivation of tubercular multifocal choroiditis.黄斑下视网膜色素上皮炎性病变表现为结核性多灶性脉络膜炎复发的体征。
BMJ Case Rep. 2021 May 24;14(5):e240280. doi: 10.1136/bcr-2020-240280.
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本文引用的文献

1
YELLOW SUBRETINAL PIGMENT EPITHELIUM DEPOSITS: A NOVEL SIGN IN OCULAR TUBERCULOSIS.黄斑下视网膜色素上皮沉积物:眼部结核病的一个新征象。
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An update on inflammatory choroidal neovascularization: epidemiology, multimodal imaging, and management.炎症性脉络膜新生血管的最新进展:流行病学、多模态成像及治疗
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Optical Coherence Tomography Features of Tuberculous Serpiginous-like Choroiditis and Serpiginous Choroiditis.结核匐行性脉络膜视网膜炎和匐行性脉络膜视网膜炎的光学相干断层扫描特征。
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Choroidal neovascularization secondary to tuberculosis: Presentation and management.结核继发脉络膜新生血管:表现与管理
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IDIOPATHIC MULTIFOCAL CHOROIDITIS PRESENTING WITH A TRANSIENT PERIPAPILLARY WHITE RING.表现为一过性视乳头周围白色环的特发性多灶性脉络膜炎
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8
Regression of peripapillary choroidal neovascular membrane in a patient with sarcoidosis after oral steroid therapy.口服类固醇治疗后结节病患者视乳头周围脉络膜新生血管膜的消退
Saudi J Ophthalmol. 2014 Apr;28(2):160-2. doi: 10.1016/j.sjopt.2014.02.007. Epub 2014 Mar 6.
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Risk of choroidal neovascularization among the uveitides.葡萄膜炎相关脉络膜新生血管的风险。
Am J Ophthalmol. 2013 Sep;156(3):468-477.e2. doi: 10.1016/j.ajo.2013.04.040. Epub 2013 Jun 21.
10
Redefining multifocal choroiditis and panuveitis and punctate inner choroidopathy through multimodal imaging.通过多模态成像重新定义多灶性脉络膜炎和全葡萄膜炎及点状内层脉络膜病变。
Retina. 2013 Jul-Aug;33(7):1315-24. doi: 10.1097/IAE.0b013e318286cc77.