a Advanced Eye Center , Post Graduate Institute of Medical Education and Research , Chandigarh , India.
b Department of Internal Medicine , Post Graduate Institute of Medical Education and Research , Chandigarh , India.
Ocul Immunol Inflamm. 2019;27(3):365-370. doi: 10.1080/09273948.2017.1373829. Epub 2017 Oct 11.
To evaluate role of ultra-wide field (UWF) versus conventional imaging in the follow-up and paradoxical worsening (PW) of tubercular (TB) multifocal serpiginoid choroiditis (MSC). Prospective observational study of patients with TB MSC undergoing UWF imaging, autofluorescence and fluorescein angiography was performed. A circle simulating central 75° field representing conventional imaging was drawn on UWF images. The information yielded by the two modalities, progression of choroiditis lesions and PW was compared. 44 eyes (29 patients, mean age: 30.7 ± 9 years; 23 males) were included. UWF imaging showed additional lesions in 39/44 eyes (88.6%). Overall, 16/44 eyes (36.4%) showed PW; 3/16 eyes (18.7%) showed only peripheral PW, while 10/16 eyes showed both central and peripheral PW. Management was altered in 11 patients (37.93%) based on UWF imaging. UWF is more useful than conventional imaging in identifying additional choroiditis lesions, PW and altering the course of therapy in TB MSC.
评估超广角 (UWF) 与传统成像在随访和结核性多灶性匐行性脉络膜炎 (TBMSC) 的矛盾性恶化 (PW) 中的作用。对接受 UWF 成像、自发荧光和荧光素血管造影检查的 TBMSC 患者进行前瞻性观察研究。在 UWF 图像上绘制一个模拟中央 75°视野的圆，代表传统成像。比较两种方式提供的信息，即脉络膜炎症病变的进展和 PW。纳入 44 只眼（29 例患者，平均年龄：30.7±9 岁；男性 23 例）。UWF 成像在 39/44 只眼（88.6%）中显示了额外的病变。总体上，16/44 只眼（36.4%）出现 PW；3/16 只眼（18.7%）仅出现周边 PW，而 10/16 只眼出现中央和周边 PW。根据 UWF 成像，11 例患者（37.93%）的治疗方案发生改变。UWF 比传统成像更能有效地识别额外的脉络膜炎症病变、PW，并改变 TBMSC 的治疗进程。
