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因慢性钙化性胰腺炎的 Frey 手术导致维生素 A 缺乏引起的干眼症。

Xerophthalmia due to vitamin A deficiency following Frey's procedure for chronic calcific pancreatitis.

机构信息

GPR-ICARE, LV Prasad Eye Institute, Hyderabad, Telangana, India.

Cornea Service, The Cornea Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India

出版信息

BMJ Case Rep. 2021 May 24;14(5):e242710. doi: 10.1136/bcr-2021-242710.

Abstract

We report a rare presentation of xerophthalmia due to partial pancreatic exocrine insufficiency following Frey's surgery (pancreatic resection) in a 12-year-old girl. The child had undergone this surgery for chronic calcific pancreatitis 3 years before and presented with ocular irritation and decreased vision of 3 months duration. Ocular examination showed severe conjunctival and corneal xerosis. Her serum retinol levels and 25-hydroxyvitamin D were tested and were extremely low. The condition rapidly reversed following high-dose replacement therapy with vitamin A and D. This case highlights the importance of continuous enzyme replacement therapy as well as dietary modification and nutritional supplement therapy and monitoring of ocular symptoms in post-pancreatic surgery.

摘要

我们报告了一例罕见的因弗雷手术(胰腺切除术)后部分胰腺外分泌功能不全导致的干性角膜结膜炎病例,患者为 12 岁女孩。该患儿 3 年前因慢性钙化性胰腺炎接受了该手术,3 个月前出现眼部刺激和视力下降。眼部检查显示严重的结膜和角膜干燥。检测其血清视黄醇水平和 25-羟维生素 D,结果极低。大剂量补充维生素 A 和 D 后,病情迅速逆转。该病例强调了胰腺手术后持续进行酶替代治疗、饮食调整和营养补充治疗以及监测眼部症状的重要性。

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